Endoscopic balloon dilatation for Crohn's strictures of the gastrointestinal tract is feasible

被引:0
作者
Karstensen, John Gasdal [1 ]
Hendel, Jakob [2 ]
Vilmann, Peter [2 ]
机构
[1] Hvidovre Univ Hosp, Dept Surg Gastroenterol, DK-2650 Hvidovre, Denmark
[2] Herlev Hosp, Dept Gastroenterol, Herlev, Denmark
来源
DANISH MEDICAL JOURNAL | 2012年 / 59卷 / 07期
关键词
DISEASE STRICTURES; DILATION; EFFICACY; SAFETY; INJECTION;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
INTRODUCTION: Despite optimized medical treatment, Crohn's disease can cause gastrointestinal (GI) strictures, which requires surgical intervention. Lately, endoscopic balloon dilatation has been established as an alternative to surgery. In the following, we report our experiences with endoscopic dilatation of strictures in the gastrointestinal tract caused by Crohn's disease. MATERIAL AND METHODS: From January 2005 to February 2011, 23 patients with Crohn's disease were referred for endoscopic dilatation. Based on data derived from this cohort, a retrospective analysis was made. Patients with Crohn's disease, obstructive GI symptoms and known bowel strictures were included. Their mean age was 39 years (2059 years) and 65% were female. Prior to the procedure, all patients had been evaluated by barium small-bowel follow through, abdominal magnetic resonance imaging and/or endoscopy. RESULTS: Dilatation was performed in 19/23 (83%) patients. During a mean follow-up period of 21 months (range 1-47 months), relapse was observed in 14/19 patients (74%). Five patients (26%) were referred to surgery due to complications (n = 1) or multiple relapses (n = 4). A total of 54 endoscopic dilatations were performed during the study period. Only one complication (perforation) was experienced, which resulted in a complication rate of 1.9%. CONCLUSION: Endoscopic dilatation in patients with Crohn's disease with obstructive GI symptoms seems safe. In three out of four patients, surgery was avoided during a mean follow- up of two years. Further optimisation of the procedure is needed to lower the rate of recurrence. FUNDING: not relevant.
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共 20 条
  • [1] ENDOSCOPIC TREATMENT OF ANASTOMOTIC STRICTURES IN CROHNS-DISEASE
    BLOMBERG, B
    ROLNY, P
    JARNEROT, G
    [J]. ENDOSCOPY, 1991, 23 (04) : 195 - 198
  • [2] Long-term evolution of disease behavior of Crohn's disease
    Cosnes, J
    Cattan, S
    Blain, A
    Beaugerie, L
    Carbonnel, F
    Parc, R
    Gendre, JP
    [J]. INFLAMMATORY BOWEL DISEASES, 2002, 8 (04) : 244 - 250
  • [3] EFFICACY AND SAFETY OF HYDROSTATIC BALLOON DILATATION OF ILEOCOLONIC CROHNS STRICTURES - A PROSPECTIVE LONG-TERM ANALYSIS
    COUCKUYT, H
    GEVERS, AM
    COREMANS, G
    HIELE, M
    RUTGEERTS, P
    [J]. GUT, 1995, 36 (04) : 577 - 580
  • [4] Effective dilation of small-bowel strictures by double-balloon enteroscopy in patients with symptomatic Crohn's disease
    Despott, Edward J.
    Gupta, Arun
    Burling, David
    Tripoli, Eric
    Konieczko, Krysia
    Hart, Ailsa
    Fraser, Chris
    [J]. GASTROINTESTINAL ENDOSCOPY, 2009, 70 (05) : 1030 - 1036
  • [5] The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management
    Dignass, A.
    Van Assche, G.
    Lindsay, J. O.
    Lemann, M.
    Soderholm, J.
    Colombel, J. F.
    Danese, S.
    D'Hoore, A.
    Gassull, M.
    Gomollon, F.
    Hommes, D. W.
    Michetti, P.
    O'Morain, C.
    Oresland, T.
    Windsor, A.
    Stange, E. F.
    Travis, S. P. L.
    [J]. JOURNAL OF CROHNS & COLITIS, 2010, 4 (01) : 28 - 62
  • [6] A pilot study of intrastricture steroid versus placebo injection after balloon dilatation of Crohn's strictures
    East, James E.
    Brooker, Jim C.
    Rutter, Matthew D.
    Saunders, Brian P.
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2007, 5 (09) : 1065 - 1069
  • [7] Safety and efficacy of endoscopic balloon dilation for treatment of Crohn's disease strictures
    Ferlitsch, A.
    Reinisch, W.
    Puespoek, A.
    Dejaco, C.
    Schillinger, M.
    Schoefl, R.
    Poetzi, R.
    Gangl, A.
    Vogelsang, H.
    [J]. ENDOSCOPY, 2006, 38 (05) : 483 - 487
  • [8] Systematic review: endoscopic dilatation in Crohn's disease
    Hassan, C.
    Zullo, A.
    De Francesco, V.
    Ierardi, E.
    Giustini, M.
    Pitidis, A.
    Taggi, F.
    Winn, S.
    Morini, S.
    [J]. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2007, 26 (11-12) : 1457 - 1464
  • [9] Krupnick A S, 2000, Semin Gastrointest Dis, V11, P41
  • [10] Long-term outcome of endoscopic pneumatic dilatation in Crohn's disease
    Morini, S
    Hassan, C
    Lorenzetti, R
    Zullo, A
    Cerro, P
    Winn, S
    Giustini, M
    Taggi, F
    [J]. DIGESTIVE AND LIVER DISEASE, 2003, 35 (12) : 893 - 897