A HIGH-DENSITY ARRAY OF 3D MICRONEEDLE-ELECTRODES FOR EVALUATION OF SPATIAL RESOLUTION OF NEURONAL ACTIVITY

被引：0

作者：

Kotani, Yuta ^{[1
]}

Sawahata, Hirohito ^{[2
]}

Yamagiwa, Shota ^{[1
]}

Numano, Rika ^{[1
]}

Koida, Kowa ^{[1
]}

Kawano, Takeshi ^{[1
]}

机构：

[1] Toyohashi Univ Technol, Toyohashi, Aichi, Japan

[2] Natl Inst Adv Ind Sci & Technol, Tokyo, Japan

来源：

2019 20TH INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS & EUROSENSORS XXXIII (TRANSDUCERS & EUROSENSORS XXXIII) | 2019年

关键词：

Microneedle-electrode array; Neuronal recording; Multichannel recording; Spatial resolution;

D O I：

10.1109/transducers.2019.8808782

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

To understand how the brain works, it is necessary to explore the behavior of the micro-scale neural network with a high spatial resolution. Here, we propose silicon growth-based microneedle-electrode arrays with the minimum electrode's interval of 150 mu m. To evaluate the spatial resolution of the neuronal signal, a 1 x 7 array of microneedle-electrodes penetrated into barrel cortex of a mouse. The spike signals recorded via the needle-electrode array were analyzed using the spike firing-rates. As the results, spatial resolution of the spike signals in the mouse's cortex is smaller than the electrode interval of 150 mu m. Therefore, such high-density array of needle-electrodes arc necessary to study the micro-scale neuronal network in the brain tissue.

引用

页码：2205 / 2208

页数：4

共 9 条

[1] In vivo neuronal action potential recordings via three-dimensional microscale needle-electrode arrays [J].