Memory reconsolidation mediates the strengthening of memories by additional learning

被引:305
作者
Lee, Jonathan L. C. [1 ]
机构
[1] Univ Birmingham, Sch Psychol, Birmingham B15 2TT, W Midlands, England
关键词
D O I
10.1038/nn.2205
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Memories are dynamic, rather than static, in nature. The reactivation of a memory through re-exposure to salient training stimuli results in its destabilization, necessitating a restabilization process known as reconsolidation, a disruption of which leads to amnesia. I found that one normal function of hippocampal memory reconsolidation in rats is to modify the strength of a contextual-fear memory as a result of further learning.
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收藏
页码:1264 / 1266
页数:3
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