Cancer of Unknown Primary Sites: What Radiologists Need to Know and What Oncologists Want to Know

被引：25
作者：
Kim, Kyung Won [1 ,2 ]
Krajewski, Katherine M. [1 ]
Jagannathan, Jyothi P. [1 ]
Nishino, Mizuki [1 ]
Shinagare, Atul B. [1 ]
Hornick, Jason L. [3 ]
Ramaiya, Nikhil H. [1 ]
机构：
[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Imaging, Boston, MA 02215 USA
[2] Seoul Asan Med Ctr, Dept Radiol, Seoul, South Korea
[3] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Pathol, Boston, MA 02215 USA
来源：
AMERICAN JOURNAL OF ROENTGENOLOGY | 2013年 / 200卷 / 03期
基金：
美国国家卫生研究院;
关键词：
carcinoma of unknown primary sites; diagnosis; imaging; immunohistochemistry; occult primary; POSITRON-EMISSION-TOMOGRAPHY; CARCINOMA; MANAGEMENT; STATISTICS; DIAGNOSIS; SEARCH; TUMORS; CT;
D O I：
10.2214/AJR.12.9363
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OBJECTIVE. In this article, we review the role of imaging in cancer of unknown primary site (CUP) diagnosis and management and the utility of immunohistochemistry, serum tumor markers, and molecular profiling in the optimized care of CUP patients. CONCLUSION. With advances in imaging, pathology, and molecular medicine, the diagnosis and management of CUP have evolved into more personalized and site-specific therapies. A multidisciplinary integrated approach among oncologists, pathologists, and radiologists is extremely important.
引用
收藏
页码：484 / 492
页数：9
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