The effects of moderate Reynolds numbers on the flow and acoustic fields of initially highly disturbed isothermal round jets at Mach number M = 0.9 and diameter-based Reynolds numbers Re-D between 2.5 x 10(4) and 2 x 10(5) are investigated using large-eddy simulation under carefully controlled conditions. To the best of our knowledge, this is the first comprehensive study of its kind. The jets originate at z = 0 from a pipe nozzle of radius r(0), in which a tripping procedure is applied to the boundary layers. At the nozzle exit, laminar-like mean velocity profiles of thickness delta similar or equal to 0.15r(0) and momentum thickness delta(theta) similar or equal to 0.018r(0), yielding Reynolds numbers Re-theta varying from 256 to 1856 depending on Re-D, and peak turbulence intensities around 9% of the jet velocity, are thus obtained. As the Reynolds number increases, the mixing layers develop more slowly, with smaller integral length scales and lower levels of velocity fluctuations. The axial profiles of turbulence intensities become smoother, showing a clear overshoot around z = 2r(0) at Re-D = 2.5 x 10(4), but a monotonical growth at Re-D = 2 x 10(5). Velocity spectra downstream of the nozzle exit also broaden with Re-D, as expected. Large-scale components usually observed in turbulent boundary layers and shear layers, characterized by Strouhal numbers St(theta) similar or equal to 0.013 around z = r(0) and by azimuthal spacings lambda(theta) similar or equal to delta, remain dominant, although the contribution of fine-scale structures with lambda(theta) <= delta/2 strengthens. Moreover, with rising Re-D, the jet potential core lengthens slightly, but the flow properties do not change significantly farther downstream. Finally, lower sound pressure levels are generated, with a decrease of about 2 dB over the range of Re-D considered. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4757667]