Nonlinear optical endoscopy based on a double-clad photonic crystal fiber and a MEMS mirror

被引：131
作者：
Fu, L
Jain, A
Xie, HK
Cranfield, C
Gu, M
机构：
[1] Swinburne Univ Technol, Fac Engn & Ind Sci, Ctr Microphoton, Hawthorn, Vic 3122, Australia
[2] Univ Florida, Dept Elect & Comp Engn, Gainesville, FL 32611 USA
来源：
OPTICS EXPRESS | 2006年 / 14卷 / 03期
关键词：
D O I：
10.1364/OE.14.001027
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Two-photon fluorescence and second harmonic generation microscopy have enabled functional and morphological in vivo imaging. However, in vivo applications of those techniques to living animals are limited by bulk optics on a bench top. Fortunately, growing functionality of fiber-optic devices and miniaturization of scanning mirrors stimulate the race to develop nonlinear optical endoscopy. In this paper, we report on a prototype of a nonlinear optical endoscope based on a double-clad photonic crystal fiber to improve the detection efficiency and a MEMS mirror to steer the light at the fiber tip. The miniaturized fiber-optic nonlinear microscope is characterized by rat esophagus imaging. Line profiles from the rat tail tendon and esophagus prove the potential of the technology in in vivo applications. (c) 2006 Optical Society of America.
引用
收藏
页码：1027 / 1032
页数：6
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