Ultrahigh-Speed Ultrahigh-Resolution Adaptive Optics - Optical Coherence Tomography System for In-vivo Small Animal Retinal Imaging

被引：0

作者：

Jian, Yifan ^{[1
]}

Xu, Jing ^{[1
]}

Zawadzki, Robert J.

Sarunic, Marinko V. ^{[1
]}

机构：

[1] Simon Fraser Univ, Burnaby, BC V5A 1S6, Canada

来源：

OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XVII | 2013年 / 8571卷

基金：

美国国家科学基金会;

关键词：

Adaptive Optics; Optical Coherence Tomography; Small Animal; RODENT RETINA; MOUSE MODEL; DEGENERATION; PERFORMANCE;

D O I：

10.1117/12.2006652

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Small animal models of human retinal diseases are a critical component of vision research. In this report, we present an ultrahigh-resolution ultrahigh-speed adaptive optics optical coherence tomography (AO-OCT) system for small animal retinal imaging (mouse, fish, etc.). We adapted our imaging system to different types of small animals in accordance with the optical properties of their eyes. Results of AO-OCT images of small animal retinas acquired with AO correction are presented. Cellular structures including nerve fiber bundles, capillary networks and detailed double-cone photoreceptors are visualized.

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