Calciphylaxis: A systematic review of existing and emerging therapies

被引:90
作者
Vedvyas, Chetan [2 ]
Winterfield, Laura S. [1 ]
Vleugels, Ruth Ann [1 ]
机构
[1] Brigham & Womens Hosp, Dept Dermatol, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
关键词
CALCIFIC UREMIC ARTERIOLOPATHY; INTRAVENOUS-SODIUM THIOSULFATE; HYPERBARIC-OXYGEN THERAPY; VASCULAR CALCIFICATION; SECONDARY HYPERPARATHYROIDISM; PROXIMAL CALCIPHYLAXIS; PERITONEAL-DIALYSIS; 1ST-LINE TREATMENT; RISK-FACTORS; CINACALCET;
D O I
10.1016/j.jaad.2011.06.009
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Calciphylaxis, also known as calcific uremic arteriolopathy, is a cutaneous ischemic small vessel vasculopathy seen in 1 to 4% of patients with chronic kidney disease on hemodialysis. It is associated with extreme pain and a 60 to 80% mortality rate in the setting of few and frequently ineffective therapeutic options, although this may be changing based on reports of success with newer therapies. (J Am Acad Dermatol 2012;67:e253-60.)
引用
收藏
页码:E253 / E260
页数:8
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