Malignant epitheloid angiomyolipoma of the kidney in a child treated with sunitinib, everolimus and axitinib

被引：8

作者：

Citak, Elvan Caglar ^{[1
]}

Yilmaz, Eda Bengi ^{[2
]}

Yaman, Emel ^{[3
]}

Kaya, Simge ^{[1
]}

Taskinlar, Hakan ^{[4
]}

Arpaci, Rabia Bozdogan ^{[5
]}

Apaydin, Demir ^{[6
]}

机构：

[1] Mersin Univ, Dept Pediat Oncol, Yenisehir, Turkey

[2] Mersin Univ, Dept Radiat Oncol, Yenisehir, Turkey

[3] Mersin Univ, Dept Med Oncol, Yenisehir, Turkey

[4] Mersin Univ, Dept Pathol, Yenisehir, Turkey

[5] Mersin Univ, Dept Pediat Surg, Yenisehir, Turkey

[6] Mersin Univ, Dept Radiol, Yenisehir, Turkey

来源：

CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL | 2015年 / 9卷 / 7-8期

关键词：

MULTICENTER;

D O I：

10.5489/cuaj.2823

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The malignant variant of epithelioid angiomyolipoma (EAML) of the kidney is uncommon, extremely aggressive and behaves like a renal cell carcinoma. We present a case of a 12-year-old male with malignant EAML who was treated according to adult treatment protocols. To our knowledge, axitinib has not been used before in children. We conclude that adult protocols, in this rare case, could be safely used in rare childhood malignancies.

引用

页码：E542 / E545

页数：4

共 9 条

[1]

[Anonymous], 2015, NATL COMPREHENSIVE C

[2]

[Anonymous], J CLIN ONCOL ASCO AN

[3]

[Anonymous], 2004, WHO CLASSIFICATION T

[4] Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial [J].

Bissler, John J. ;

Kingswood, J. Christopher ;

Radzikowska, Elzbieta ;

Zonnenberg, Bernard A. ;

Frost, Michael ;

Belousova, Elena ;

Sauter, Matthias ;

Nonomura, Norio ;

Brakemeier, Susanne ;

de Vries, Petrus J. ;

Whittemore, Vicky H. ;

Chen, David ;

Sahmoud, Tarek ;

Shah, Gaurav ;

Lincy, Jeremie ;

Lebwohl, David ;

Budde, Klemens .

LANCET, 2013, 381 (9869) :817-824

[5]

Blank CU, 2012, J CLIN ONCOL, V402, P30

[6] Pure epitheliod perivascular epitheloid cell tumor (epitheliod angiomyolipoma) of kidney: Case report and literature review [J].

Jayaprakash, P. G. ;

Mathews, Susan ;

Azariah, M. Biju ;

Babu, Geethu .

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2014, 10 (02) :404-406

[7]

Koh Y, 2012, J CLIN ONCOL, V30

[8] Multicenter phase II study of sunitinib in patients with non-clear cell renal cell carcinoma [J].

Lee, J. -L. ;

Ahn, J. -H. ;

Lim, H. Y. ;

Park, S. H. ;

Lee, S. H. ;

Kim, T. M. ;

Lee, D. -H. ;

Cho, Y. M. ;

Song, C. ;

Hong, J. H. ;

Kim, C. -S. ;

Ahn, H. .

ANNALS OF ONCOLOGY, 2012, 23 (08) :2108-2114

[9] Fatal malignant metastastic epithelioid angiomyolipoma presenting in a young woman: case report and review of the literature [J].

Wyluda, Edward ;

Baquero, Giselle ;

Lamparella, Nicholas ;

Abendroth, Catherine ;

Drabick, Joseph .

RARE TUMORS, 2013, 5 (03) :154-156

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