Cutaneous complications of erlotinib in the treatment of non-small cell lung cancer

被引:0
|
作者
Preda, V. [1 ]
Mann, S. [2 ]
Lee, S. [3 ]
机构
[1] Skin & Canc Fdn Australia, Darlinghurst, NSW 2010, Australia
[2] Histopath, Sydney, NSW, Australia
[3] Univ Sydney, Sydney, NSW 2006, Australia
来源
关键词
acne-like; epithelial; neoplasia; paronychia; xerosis;
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
With the rapid expansion in knowledge concerning oncogenesis, targeted pharmacotherapies inhibiting tumour growth are emerging. This article alms to raise awareness of the dermatological side-effect profile of erlotinib. Erlotinib is a tyrosine kinase inhibitor of epidermal growth-factor receptor (EGFR) and is employed in the treatment of non-small cell lung cancer. We describe the dermatological side-effects of erlotinib, with particular attention to the clinical and histological features of its acne-like eruption. Patient comfort and compliance will be significantly enhanced by the early detection and treatment of side-effects from EGFR inhibitors.
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收藏
页码:133 / 141
页数:9
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