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Cutaneous complications of erlotinib in the treatment of non-small cell lung cancer
被引:0
|作者:
Preda, V.
[1
]
Mann, S.
[2
]
Lee, S.
[3
]
机构:
[1] Skin & Canc Fdn Australia, Darlinghurst, NSW 2010, Australia
[2] Histopath, Sydney, NSW, Australia
[3] Univ Sydney, Sydney, NSW 2006, Australia
来源:
关键词:
acne-like;
epithelial;
neoplasia;
paronychia;
xerosis;
D O I:
暂无
中图分类号:
R75 [皮肤病学与性病学];
学科分类号:
100206 ;
摘要:
With the rapid expansion in knowledge concerning oncogenesis, targeted pharmacotherapies inhibiting tumour growth are emerging. This article alms to raise awareness of the dermatological side-effect profile of erlotinib. Erlotinib is a tyrosine kinase inhibitor of epidermal growth-factor receptor (EGFR) and is employed in the treatment of non-small cell lung cancer. We describe the dermatological side-effects of erlotinib, with particular attention to the clinical and histological features of its acne-like eruption. Patient comfort and compliance will be significantly enhanced by the early detection and treatment of side-effects from EGFR inhibitors.
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页码:133 / 141
页数:9
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