An outbreak of hepatitis A amongst injecting drug users

被引:32
作者
O'Donovan, D
Cooke, RPD [1 ]
Joce, R
Eastbury, A
Waite, J
Stene-Johansen, K
机构
[1] Eastbourne Hosp NHS Trust, Dept Med Microbiol, Eastbourne BN21 2UD, E Sussex, England
[2] Eastbourne Borough Council, Hlth & Housing Dept, Eastbourne BN21 4UH, E Sussex, England
[3] Brighton Hove Hlth Author, Dept Publ Hlth Med, Lewes BN7 2PB, E Sussex, England
[4] Community Drugs Team, Eastbourne BN21 2BQ, E Sussex, England
[5] Natl Inst Publ Hlth, Dept Virol, N-0403 Oslo, Norway
关键词
D O I
10.1017/S0950268801006185
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This descriptive study investigated an outbreak of hepatitis A virus (HAV) infection among injecting drug users (IDUs) and their contacts. Twenty-seven cases of acute HAV infection were identified in a 5-month period. Connections with the local injecting drug using (IDU) population were established for 25 of the cases of whom 14 admitted to injecting drug use. HAV RNA genotyping revealed two HAV variants, closely related to variants found in Scandinavian IDUs and in South East Asia. The study demonstrates that once HAV enters the IDU population extensive outbreaks are possible. We recommend that all IDUs should be tested for HAV and hepatitis B virus (HBV) infections and offered combined hepatitis A and B vaccines if non-immune.
引用
收藏
页码:469 / 473
页数:5
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