Reduced-intensity conditioning allogeneic transplantation is associated with a high incidence of extramedullary relapses in multiple myeloma patients

被引：76

作者：

Pérez-Simón, JA

Sureda, A

Fernández-Aviles, F

Sampol, A

Cabrera, JR

Caballero, D

Martino, R

Petit, J

Tomás, JF

Moraleda, JM

Alegre, A

Cañizo, C

Brunet, S

Rosiñol, L

Lahuerta, J

Díez-Martín, JL

León, A

García, A

Vazquez, L

Sierra, J

San Miguel, JF

机构：

[1] Hosp Clin Univ, Salamanca, Spain

[2] Hosp Santa Creu I Sant Pau, Barcelona, Spain

[3] Hosp Clin Barcelona, Barcelona, Spain

[4] Hosp Son Dureta, Barcelona, Spain

[5] Hosp Puerta Hierro, Madrid, Spain

[6] Inst Catalan Oncol, Barcelona, Spain

[7] Fdn Jimenez Diaz, E-28040 Madrid, Spain

[8] Hosp Morales Meseguer, Murcia, Spain

[9] Hosp Princesa, Madrid, Spain

[10] Hosp 12 Octubre, E-28041 Madrid, Spain

[11] Hosp Gen Gregorio Maranon, Madrid, Spain

[12] Hosp Jerez, Jerez de la Frontera, Spain

来源：

LEUKEMIA | 2006年 / 20卷 / 03期

关键词：

D O I：

10.1038/sj.leu.2404085

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：542 / 545

页数：5

共 8 条

[1] Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma:: an analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT [J].

Crawley, C ;

Lalancette, M ;

Szydlo, R ;

Gilleece, M ;

Peggs, K ;

Mackinnon, S ;

Juliusson, G ;

Ahlberg, L ;

Nagler, A ;

Shimoni, A ;

Sureda, A ;

Boiron, JM ;

Einsele, H ;

Chopra, R ;

Carella, A ;

Cavenagh, J ;

Gratwohl, A ;

Garban, F ;

Zander, A ;

Björkstrand, B ;

Niederwieser, D ;

Gahrton, G ;

Apperley, JF .

BLOOD, 2005, 105 (11) :4532-4539

[2] ALLOGENEIC BONE-MARROW TRANSPLANTATION IN MULTIPLE-MYELOMA [J].

GAHRTON, G ;

TURA, S ;

LJUNGMAN, P ;

BELANGER, C ;

BRANDT, L ;

CAVO, M ;

FACON, T ;

GRANENA, A ;

GORE, M ;

GRATWOHL, A ;

LOWENBERG, B ;

NIKOSKELAINEN, J ;

REIFFERS, JJ ;

SAMSON, D ;

VERDONCK, L ;

VOLIN, L .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (18) :1267-1273

[3] Progress in allogeneic bone marrow and peripheral blood stem cell transplantation for multiple myeloma:: a comparison between transplants performed 1983-93 and 1994-98 at European Group for Blood and Marrow Transplantation centres [J].

Gahrton, G ;

Svensson, H ;

Cavo, M ;

Apperley, J ;

Bacigalupo, A ;

Björkstrand, B ;

Bladé, J ;

Cornelissen, J ;

de Laurenzi, A ;

Facon, T ;

Ljungman, P ;

Michallet, M ;

Niederwieser, D ;

Powles, R ;

Reiffers, J ;

Russell, NH ;

Samson, D ;

Schaefer, UW ;

Schattenberg, A ;

Tura, S ;

Verdonck, LF ;

Vernant, JP ;

Willemze, R ;

Volin, L .

BRITISH JOURNAL OF HAEMATOLOGY, 2001, 113 (01) :209-216

[4] Relapse to prior autograft and chronic graft-versus-host disease are the strongest prognostic factors for outcome of melphalan/fludarabine-based dose-reduced allogeneic stem cell transplantation in patients with multiple myeloma [J].

Kröger, N ;

Perez-Simon, JA ;

Myint, H ;

Klingemann, H ;

Shimoni, A ;

Nagler, A ;

Martino, R ;

Alegre, A ;

Tomas, JF ;

Schwerdtfeger, R ;

Kiehl, M ;

Fauser, A ;

Sayer, HG ;

Leon, A ;

Beyer, J ;

Zabelina, T ;

Ayuk, F ;

San Miguel, JF ;

Brand, R ;

Zander, AR .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2004, 10 (10) :698-708

[5] Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantation [J].

Kröger, N ;

Schilling, G ;

Einsele, H ;

Liebisch, P ;

Shimoni, A ;

Nagler, A ;

Perez-Simon, JA ;

San Miguel, JF ;

Kiehl, M ;

Fauser, A ;

Schwerdtfeger, R ;

Wandt, H ;

Sayer, HG ;

Myint, H ;

Klingemann, H ;

Zabelina, T ;

Dierlamm, J ;

Hinke, A ;

Zander, AR .

BLOOD, 2004, 103 (11) :4056-4061

[6] Molecular remission after allogeneic or autologous transplantation of hematopoietic stem cells for multiple myeloma [J].

Martinelli, G ;

Terragna, C ;

Zamagni, E ;

Ronconi, S ;

Tosi, P ;

Lemoli, RM ;

Bandini, G ;

Motta, MR ;

Testoni, N ;

Amabile, M ;

Ottaviani, E ;

Vianelli, N ;

de Vivo, A ;

Gozzetti, A ;

Tura, S ;

Cave, M .

JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (11) :2273-2281

[7] Chronic but not acute graft-versus-host disease improves outcome in multiple myeloma patients after non-myeloablative allogeneic transplantation [J].

Pérez-Simón, JA ;

Martino, R ;

Alegre, A ;

Tomás, JF ;

De Leon, A ;

Caballero, D ;

Sureda, A ;

Sierra, J ;

San Miguel, JF .

BRITISH JOURNAL OF HAEMATOLOGY, 2003, 121 (01) :104-108

[8] Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors [J].

Rasmussen, T ;

Kuehl, M ;

Lodahl, M ;

Johnsen, HE ;

Dahl, IMS .

BLOOD, 2005, 105 (01) :317-323

← 1 →