Gold-catalyzed formation of aryl-fused pyrazolooxazepines via intramolecular regioselective 7-exo-dig cyclization

被引：7
|
作者：
Guduru, Ravinder [1 ,2 ]
Mangina, N. S. V. M. Rao [1 ,2 ]
Sridhar, Balasubramanian [3 ]
Karunakar, Galla V. [1 ,2 ]
机构：
[1] Indian Inst Chem Technol, CSIR, Div Fluoro & Agrochem, Hyderabad 500007, Andhra Pradesh, India
[2] Acad Sci & Innovat Res, Ghaziabad 201002, India
[3] Indian Inst Chem Technol, CSIR, Ctr Xray Crystallog, Hyderabad 500007, Andhra Pradesh, India
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 10期
关键词：
PROPARGYLIC BETA-ENAMINONES; 3-COMPONENT SYNTHESIS; ONE-POT; RINGS; AMINO;
D O I：
10.1039/c8ob03157f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method was developed for the synthesis of substituted aryl-fused pyrazolooxazepines from ortho-O-propargyl aryl pyrazoles by gold catalysis. In this organic transformation a new C-N bond was formed regioselectively via 7-exo-dig cyclization. Moderate to good yields of aryl-fused pyrazolooxazepine derivatives were obtained with significant molecular complexity in one-pot.
引用
收藏
页码：2809 / 2817
页数：9
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