Cardiorenal Syndrome Type 5: Clinical Presentation, Pathophysiology and Management Strategies from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)

被引：30

作者：

Mehta, Ravindra L. ^{[1
]}

Rabb, Hamid ^{[2
]}

Shaw, Andrew D. ^{[3
]}

Singbartl, Kai ^{[4
]}

Ronco, Claudio ^{[5
]}

McCullough, Peter A. ^{[6
,7
,8
,9
,10
]}

Kellum, John A. ^{[11
]}

机构：

[1] Univ Calif San Diego, Dept Med, San Diego, CA 92103 USA

[2] Johns Hopkins Univ, Dept Med, Baltimore, MD USA

[3] Duke Univ, Med Ctr, Dept Anesthesiol, Durham, NC 27710 USA

[4] Penn State Coll Med, Milton S Hershey Med Ctr, Dept Anesthesiol, Hershey, PA USA

[5] San Bortolo Hosp, Dept Nephrol, Int Renal Res Inst IRRIV, Vicenza, Italy

[6] St John Providence Hlth Syst, Warren, MI USA

[7] Providence Hosp & Med Ctr, Southfield, MI USA

[8] Providence Hosp & Med Ctr, Novi, MI USA

[9] St John Macomb Oakland Ctr, Madison Hts, MI USA

[10] St John Hosp & Med Ctr, Detroit, MI USA

[11] Univ Pittsburgh, Dept Crit Care Med, Clin Res Invest & Syst Modeling Acute Illnes CRIS, Pittsburgh, PA USA

来源：

ADQI CONSENSUS ON AKI BIOMARKERS AND CARDIORENAL SYNDROMES | 2013年 / 182卷

关键词：

ACUTE KIDNEY INJURY; CRITICALLY-ILL PATIENTS; HIGH-VOLUME HEMOFILTRATION; ACUTE LUNG INJURY; RENAL BLOOD-FLOW; SEPTIC SHOCK; SEVERE SEPSIS; FLUID ACCUMULATION; ANGIOTENSIN-II; OXYGEN-TRANSPORT;

D O I：

10.1159/000349970

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiorenal syndrome type 5 (CRS-5) includes conditions where there is a simultaneous involvement of the heart and kidney from a systemic disorder. Given the wide spectrum of diseases that contribute to CRS-5, several pathophysiological mechanisms are invoked representing the response of the heart and kidney to the contributing disorder that is ongoing. The nature, duration and the underlying condition of the heart and kidney strongly influence the clinical course of CRS-5. In this paper we discuss the pathophysiology of CRS-5 in the setting of sepsis as a model system for CRS-5 providing a brief overview of strategies for monitoring and therapeutic intervention. We offer a framework for reference for considering other disorders leading to CRS-5 where the development of cardiac and renal dysfunction is more insidious. Copyright (C) 2013 S. Karger AG, Basel

引用

页码：174 / +

页数：6

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