Liverworts-Potential Source of Medicinal Compounds

被引:81
作者
Asakawa, Y. [1 ]
机构
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan
关键词
Marchantiophyta; liverwort; terpenoids; phenolics; aroma; bitterness; cytotoxicity; anti-obesity;
D O I
10.2174/138161208786404272
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The bryophytes contain the Marchantiophyta (liverworts), Bryophyta (mosses) and Anthocerotophyta (hornworts) among which the Marchantiophyta contain cellular oil body and they produce a number of terpenoids, aromatic compounds and acetogenins, several of which show interesting biological activity such as allergenic contact dermatitis, insecticide, insect antifeedant, cytotoxic, piscicidal, muscle relaxing, plant growth regulatory, anti-HIV, DNA polymerase inhibitory, anti-obesity, neurotrophic, NO production inhibitory, antimicrobial and antifungal activities. The isolation and chemical structures of biologically active compounds and their total synthesis are reviewed.
引用
收藏
页码:3067 / 3088
页数:22
相关论文
共 94 条
[1]   Hodgsonox, a new class of sesquiterpene from the liverwort Lepidolaena hodgsoniae.: Isolation directed by insecticidal activity [J].
Ainge, GD ;
Gerard, PJ ;
Hinkley, SFR ;
Lorimer, SD ;
Weavers, RT .
JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (08) :2818-2821
[2]  
Ando H, 1984, ADV BRYOLOGY, V2, P133
[3]   CHEMOSYSTEMATICS OF BRYOPHYTES .17. OCCURRENCE OF A POTENT PISCICIDAL DITERPENEDIAL IN THE LIVERWORT RICCARDIA-LOBATA VAR YAKUSHIMENSIS [J].
ASAKAWA, Y ;
HARRISON, LJ ;
TOYOTA, M .
PHYTOCHEMISTRY, 1985, 24 (02) :261-262
[4]   Chemosystematics of the Hepaticae [J].
Asakawa, Y .
PHYTOCHEMISTRY, 2004, 65 (06) :623-669
[5]   TERPENOIDS FROM THE FRENCH LIVERWORT TARGIONIA-HYPOPHYLLA [J].
ASAKAWA, Y ;
TOYOTA, M ;
CHEMINAT, A .
PHYTOCHEMISTRY, 1986, 25 (11) :2555-2556
[6]   Recent advances in phytochemistry of bryophytes-acetogenins, terpenoids and bis(bibenzyl)s from selected Japanese, Taiwanese, New Zealand, Argentinean and European liverworts [J].
Asakawa, Y .
PHYTOCHEMISTRY, 2001, 56 (03) :297-312
[7]  
Asakawa Y., 1990, Bryophyte development: physiology and biochemistry., P259
[8]  
ASAKAWA Y, 1982, PROG CH ORG NAT PROD, V42, P1
[9]  
Asakawa Y., 1990, Proceedings of the Phytochemical Society of Europe, V29, P369
[10]  
ASAKAWA Y, 2004, AROMA RES, V15, P204