Susceptibility Weighted Imaging at Ultra High Magnetic Field Strengths: Theoretical Considerations and Experimental Results

被引:123
作者
Deistung, Andreas [1 ]
Rauscher, Alexander [2 ]
Sedlacik, Jan [3 ]
Stadler, Joerg [4 ]
Witoszynskyj, Stephan [5 ]
Reichenbach, Juergen R. [1 ]
机构
[1] Friedrich Schiller Univ Jena, Univ Clin, Inst Diagnost & Intervent Radiol, Med Phys Grp, D-07743 Jena, Germany
[2] UBC MRI Res Ctr, Vancouver, BC, Canada
[3] St Jude Childrens Hosp, Div Translat Imaging Res, Dept Radiol Sci, Memphis, TN 38105 USA
[4] Leibniz Inst Neurobiol, Magdeburg, Germany
[5] Med Univ Vienna, Dept Diagnost Radiol, Vienna, Austria
关键词
MRI; SWI; magnetic susceptibility; phase; 7T;
D O I
10.1002/mrm.21754
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
We present numerical simulations and experimental results for susceptibility weighted imaging (SWI) at 7 T. Magnitude, phase, and SWI contrast were simulated for different voxel geometries and imaging parameters, resulting in an echo time of 14 msec for optimum contrast between veins and surrounding tissue. Slice thickness of twice the in-plane voxel size or more resulted in optimum vessel visibility. Phantom and in vivo data are in very good agreement with the simulations and the delineation of vessels at 7 T was superior compared to lower field strengths. The phase of the complex data reveals anatomical details that are complementary to the corresponding magnitude images. Susceptibility weighted imaging at very high field strengths is a promising technique because of its high sensitivity to tissue susceptibility, its low specific absorption rate, and the phase's negligible sensitivity to B, inhomogeneities. Magn Reson Med 60:1155-1168, 2008. (C) 2008 Wiley-Liss.
引用
收藏
页码:1155 / 1168
页数:14
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