Complete Genome Sequence of Wide-Host-Range Staphylococcus aureus Phage JD007

被引：20

作者：

Cui, Zelin ^{[1
]}

Song, Zhen ^{[2
]}

Wang, Yanchun ^{[1
]}

Zeng, Lingbin ^{[1
]}

Shen, Wenbin ^{[1
]}

Wang, Zheng ^{[1
]}

Li, Qingtian ^{[2
]}

He, Ping ^{[1
]}

Qin, Jinhong ^{[1
]}

Guo, Xiaokui ^{[1
,2
]}

机构：

[1] Shanghai Jiao Tong Univ, Dept Med Microbiol & Parasitol, Inst Med Sci, Sch Med, Shanghai 200030, Peoples R China

[2] Shanghai Jiao Tong Univ, Dept Lab Med, Ruijin Hosp, Sch Med, Shanghai 200030, Peoples R China

来源：

JOURNAL OF VIROLOGY | 2012年 / 86卷 / 24期

基金：

国家高技术研究发展计划(863计划); 中国国家自然科学基金;

关键词：

THERAPY;

D O I：

10.1128/JVI.02728-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Methicillin-resistant Staphylococcus aureus-related infections have become a serious problem worldwide. Bacteriophage therapy is an alternative approach against this threat. S. aureus phage JD007, which belongs to the Myoviridae family according to transmission electron microscopic imaging, could lyse nearly 30% of the S. aureus strains from Ruijin Hospital, Shanghai, China, and was isolated from chicken feces in Shanghai, China. The complete genome showed that JD007 is a linear, double-stranded DNA phage 141,836 bp in length with a GC content of 30.4% encoding 217 open reading frames. A BLAST search of the JD007 genome revealed that it was very similar to that of phage GH15.

引用

收藏

页码：13880 / 13881

页数：2

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