Drug design - Chemistry and biology

被引：2
作者：
Sawyer, TK [1 ]
机构：
[1] ARIAD Pharmaceut, Cambridge, MA USA
来源：
BIOTECHNIQUES | 2001年 / 31卷 / 05期
关键词：
D O I：
10.2144/01315dd01
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：1164 / +
页数：5
相关论文
共 80 条
[1]  
AHAGYAN R, 2001, CURR OPIN CHEM BIOL, V5, P375
[2]  
Antel J, 1999, Curr Opin Drug Discov Devel, V2, P224
[3]   BCX-1812 (RWJ-270201): Discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design [J].
Babu, YS ;
Chand, P ;
Bantia, S ;
Kotian, P ;
Dehghani, A ;
El-Kattan, Y ;
Lin, TH ;
Hutchison, TL ;
Elliott, AJ ;
Parker, CD ;
Ananth, SL ;
Horn, LL ;
Laver, GW ;
Montgomery, JA .
JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (19) :3482-3486
[4]  
Beeley L J, 2000, Prog Med Chem, V37, P1, DOI 10.1016/S0079-6468(08)70056-0
[5]  
Bohacek R, 1999, IMA V MATH, V108, P103
[6]   Modern computational chemistry and drug discovery: structure generating programs [J].
Bohacek, RS ;
McMartin, C .
CURRENT OPINION IN CHEMICAL BIOLOGY, 1997, 1 (02) :157-161
[7]   Structure-based library design:: molecular modelling merges with combinatorial chemistry [J].
Böhm, HJ ;
Stahl, M .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2000, 4 (03) :283-286
[8]   Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures [J].
Bolin, DR ;
Swain, AL ;
Sarabu, R ;
Berthel, SJ ;
Gillespie, P ;
Huby, NJS ;
Makofske, R ;
Orzechowski, L ;
Perrotta, A ;
Toth, K ;
Cooper, JP ;
Jiang, N ;
Falcioni, F ;
Campbell, R ;
Cox, D ;
Gaizband, D ;
Belunis, CJ ;
Vidovic, D ;
Ito, K ;
Crowther, R ;
Kammlott, U ;
Zhang, XL ;
Palermo, R ;
Weber, D ;
Guenot, J ;
Nagy, Z ;
Olson, GL .
JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (11) :2135-2148
[9]   Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design [J].
Bressi, JC ;
Verlinde, CLMJ ;
Aronov, AM ;
Le Shaw, M ;
Shin, SS ;
Nguyen, LN ;
Suresh, S ;
Buckner, FS ;
Van Voorhis, WC ;
Kuntz, ID ;
Hol, WGJ ;
Gelb, MH .
JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (13) :2080-2093
[10]   Chemogenomic approaches to drug discovery - Commentary [J].
Caron, PR ;
Mullican, MD ;
Mashal, RD ;
Wilson, KP ;
Su, MS ;
Murcko, MA .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2001, 5 (04) :464-470
12345678