Malaria control in Malawi: Current status and directions for the future

被引:52
作者
Mathanga, Don P. [2 ,3 ]
Walker, Edward D. [4 ]
Wilson, Mark L. [5 ]
Ali, Doreen
Taylor, Terrie E. [6 ,7 ]
Laufer, Miriam K. [1 ]
机构
[1] Univ Maryland, Ctr Vaccine Dev, Sch Med, Baltimore, MD 21201 USA
[2] Univ Malawi, Dept Community Hlth, Coll Med, Blantyre, Malawi
[3] Univ Malawi, Malaria Alert Ctr, Coll Med, Blantyre, Malawi
[4] Michigan State Univ, Dept Microbiol & Mol Genet, E Lansing, MI 48824 USA
[5] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA
[6] Michigan State Univ, Coll Osteopath Med, Dept Internal Med, E Lansing, MI 48824 USA
[7] Univ Malawi, Blantyre Malaria Project, Coll Med, Blantyre, Malawi
关键词
Epidemiology; Malaria; Anopheles; Malawi; Artemisinin based combination therapy; Insecticide treated nets; Indoor residual spraying; PLASMODIUM-FALCIPARUM MALARIA; CEREBRAL MALARIA; NORTHERN MALAWI; AGE; RETINOPATHY; SELECTION; BLANTYRE; INFANTS;
D O I
10.1016/j.actatropica.2011.06.017
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The last decade has seen an increase in investment and concerted efforts by the Malawi Ministry of Health and partners to control malaria disease. This report summarizes what is known about the burden of malaria and the strategies being implemented to control it in Malawi. Over the past 5 years, roll out of treatment and prevention efforts have been successful in the country, as demonstrated by increased use of insecticide treated nets, improved access to prompt and effective treatment and the initiation of pilot studies of indoor residual spraying. However, unlike other countries in the region, the recent data have not suggested a decrease in the burden of disease. We describe the environment in which the activities of Malawi's International Center for Excellence in Malaria Research (ICEMR) will be carried out and provide the rationale for the clinical, entomological and molecular studies. Our approach is to establish consistent, stainable data collection systems that are embedded within the public health sector. Through standardized and long-term studies of hosts, parasites and vectors, we hope to contribute to assessment of malaria disease burden, the appropriate application of interventions and policies and provide both the data collection and the health care infrastructure to ultimately eliminate the disease. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:212 / 217
页数:6
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