Relationship between Uveitis and Thyroid Disease: A 13-Year Nationwide Population-based Cohort Study in Taiwan

被引：2

作者：

Lin, Chun-Ju ^{[1
,2
,3
]}

Tien, Peng-Tai ^{[1
,4
]}

Chang, Cheng-Hsien ^{[1
,2
,3
]}

Hsia, Ning-Yi ^{[1
]}

Yang, Yu-Cih ^{[5
,6
]}

Lai, Chun-Ting ^{[1
]}

Bair, Henry ^{[1
,7
]}

Chen, Huan-Sheng ^{[8
]}

Tsai, Yi-Yu ^{[1
,2
,3
]}

机构：

[1] China Med Univ, China Med Univ Hosp, Dept Ophthalmol, 2 Yuh Der Rd, Taichung 40447, Taiwan

[2] China Med Univ, Coll Med, Sch Med, Taichung, Taiwan

[3] Asia Univ, Dept Optometry, Taichung, Taiwan

[4] China Med Univ, Coll Med, Grad Inst Clin Med Sci, Taichung, Taiwan

[5] China Med Univ Hosp, Management Off Hlth Data, Taichung, Taiwan

[6] China Med Univ, Coll Med, Taichung, Taiwan

[7] Stanford Univ, Sch Med, Stanford, CA 94305 USA

[8] NephroCare Ltd, An Shin Dialysis Ctr, Fresenius Med Care, Taichung, Taiwan

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2021年 / 29卷 / 7-8期

关键词：

Age; diabetes mellitus; gender; hypertension; lipid disorders; thyroid disease; uveitis; ASSOCIATION; HYPERTHYROIDISM; EPIDEMIOLOGY; DYSFUNCTION; UACA;

D O I：

10.1080/09273948.2020.1762899

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose To investigate whether patients with thyroid disease are at increased risk of uveitis. Methods Data was collected from the Taiwan National Health Insurance system and included patients newly diagnosed with thyroid disease from 2000 to 2012. The endpoint of interest was a diagnosis of uveitis. Results In analyzing 21,396 patients with thyroid disease, yielding 85,584 matched comparisons, patients with thyroid disease to have a significantly higher cumulative incidence of uveitis when compared to the control cohort with the Kaplan-Meier analysis. This result was further confirmed by Cox regression analysis. The increased risk was persistent in both genders. The association between thyroid disease and uveitis was stronger in patients without diabetes or hypertension. Conclusion Patients with thyroid disease were found to have a higher risk for uveitis. For certain age groups or patients without diabetes or hypertension, the role of thyroid disease might be more crucial for uveitis development.

引用

页码：1292 / 1298

页数：7

共 37 条

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