Single-Molecule Plasmonic Optical Trapping

被引：73

作者：

Zhan, Chao ^{[1
]}

Wang, Gan ^{[1
]}

Yi, Jun ^{[1
]}

Wei, Jun-Ying ^{[1
]}

Li, Zhi-Hao ^{[1
]}

Chen, Zhao-Bin ^{[1
]}

Shi, Jia ^{[1
]}

Yang, Yang ^{[1
]}

Hong, Wenjing ^{[1
]}

Tian, Zhong-Qun ^{[1
]}

机构：

[1] Xiamen Univ, Pen Tung Sah Inst Micronano Sci & Technol, Collaborat Innovat Ctr Chem Energy Mat iChEM, Coll Chem & Chem Engn,State Key Lab Phys Chem Sol, Xiamen 361005, Peoples R China

来源：

MATTER | 2020年 / 3卷 / 04期

基金：

中国国家自然科学基金;

关键词：

MANIPULATION; TWEEZERS; FORCE; CONDUCTANCE; ELECTRONICS; PARTICLES; JUNCTIONS; DESIGN;

D O I：

10.1016/j.matt.2020.07.019

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The volume of the object that can be manipulated in solution is continuously decreasing toward an ultimate goal of a single molecule. However, Brownian motions suppress the molecular trapping. To date, free-molecule trapping in solution has not been accomplished. Here, we develop a strategy to directly trap, investigate, and release single molecules (similar to 2 nm) in solution by using an adjustable plasmonic optical nanogap, which has been further applied for selective single-molecule trapping. Comprehensive experiments and theoretical simulations demonstrated that the trapping force originated from plasmonic nanomaterials. This technique opens an avenue to manipulate single molecules and other objects in the size range of primary interest for physics, chemistry, and life and material sciences without the limitations of strong bonding group, ultra-high vacuum, and ultra-low temperature, and makes possible controllable single-molecule manipulation and investigation as well as bottom-up construction of nanodevices and molecular machines.

引用

页码：1350 / 1360

页数：11

共 59 条

[1] Direct observation of base-pair stepping by RNA polymerase [J].