Epidemiology of Hospitalized Heart Failure Differences and Similarities Between Patients with Reduced versus Preserved Ejection Fraction

被引:8
作者
Vaduganathan, Muthiah [1 ]
Fonarow, Gregg C. [2 ]
机构
[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA
[2] Ronald Reagan UCLA Med Ctr, Ahmanson UCLA Cardiomyopathy Ctr, Div Cardiol, Los Angeles, CA 90095 USA
基金
美国医疗保健研究与质量局;
关键词
Acute heart failure; Preserved ejection fraction; Epidemiology; Outcomes; SYSTOLIC FUNCTION; SUBSEQUENT MORTALITY; NATIONAL TRENDS; OUTCOMES; RATES; REHOSPITALIZATION; PREVALENCE; ADMISSION; DEATH; STAY;
D O I
10.1016/j.hfc.2013.04.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Annually, more than 1 million patients are hospitalized for heart failure (HF), translating to high healthcare utilization and cost burden. Among patients with hospitalized HF (HHF), approximately 50% have HF with preserved ejection fraction (HFpEF) and 50% have HF with reduced ejection fraction (HFrEF), with the proportion of patients with HFpEF increasing with time. This article defines the epidemiologic landscape of patients with HHF, comparing and contrasting those with HFpEF and HFrEF, and identifies key areas that require further investigation. More complete characterization of these populations may be the first step to developing effective therapies.
引用
收藏
页码:271 / +
页数:7
相关论文
共 35 条
[1]   Incident heart failure hospitalization and subsequent mortality in chronic heart failure: A propensity-matched study [J].
Ahmed, Ali ;
Allman, Richard M. ;
Fonarow, Gregg C. ;
Love, Thomas E. ;
Zannad, Faiez ;
Dell'Italia, Louis J. ;
White, Michel ;
Gheorghiade, Mihai .
JOURNAL OF CARDIAC FAILURE, 2008, 14 (03) :211-218
[2]   Effects of digoxin on morbidity and mortality in diastolic heart failure: The ancillary Digitalis Investigation Group trial [J].
Ahmed, Ali ;
Rich, Michael W. ;
Fleg, Jerome L. ;
Zile, Michael R. ;
Young, James B. ;
Kitzman, Dalane W. ;
Love, Thomas E. ;
Aronow, Wilbert S. ;
Adams, Kirkwood F., Jr. ;
Gheorghiade, Mihai .
CIRCULATION, 2006, 114 (05) :397-403
[3]   The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis [J].
Berry, C. ;
Doughty, R. N. ;
Granger, C. ;
Kober, L. ;
Massie, B. ;
McAlister, F. ;
McMurray, J. ;
Pocock, S. ;
Poppe, K. ;
Swedberg, K. ;
Somaratne, J. ;
Whalley, G. A. ;
Ahmed, A. ;
Andersson, B. ;
Bayes-Genis, A. ;
Berry, C. ;
Cowie, M. ;
Cubbon, R. ;
Doughty, R. N. ;
Ezekowitz, J. ;
Gonzalez-Juanatey, J. ;
Gorini, M. ;
Gotsman, I. ;
Grigorian-Shamagian, L. ;
Guazzi, M. ;
Kearney, M. ;
Kober, L. ;
Komajda, M. ;
di Lenarda, A. ;
Lenzen, M. ;
Lucci, D. ;
Macin, S. ;
Madsen, B. ;
Maggioni, A. ;
Martinez-Selles, M. ;
McAlister, F. ;
Oliva, F. ;
Poppe, K. ;
Rich, M. ;
Richards, M. ;
Senni, M. ;
Squire, I. ;
Taffet, G. ;
Tarantini, L. ;
Tribouilloy, C. ;
Troughton, R. ;
Tsutsui, H. ;
Whalley, G. A. ;
Doughty, R. N. ;
Earle, N. .
EUROPEAN HEART JOURNAL, 2012, 33 (14) :1750-1757
[4]   Outcome of heart failure with preserved ejection fraction in a population-based study [J].
Bhatia, R. Sacha ;
Tu, Jack V. ;
Lee, Douglas S. ;
Austin, Peter C. ;
Fang, Jiming ;
Haouzi, Annick ;
Gong, Yanyan ;
Liu, Peter P. .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (03) :260-269
[5]   Heart Failure-Associated Hospitalizations in the United States [J].
Blecker, Saul ;
Paul, Margaret ;
Taksler, Glen ;
Ogedegbe, Gbenga ;
Katz, Stuart .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (12) :1259-1267
[6]  
Brouwers FP, EUR HEART J IN PRESS
[7]   Trends in Length of Stay and Short-term Outcomes Among Medicare Patients Hospitalized for Heart Failure, 1993-2006 [J].
Bueno, Hector ;
Ross, Joseph S. ;
Wang, Yun ;
Chen, Jersey ;
Vidan, Maria T. ;
Normand, Sharon-Lise T. ;
Curtis, Jeptha P. ;
Drye, Elizabeth E. ;
Lichtman, Judith H. ;
Keenan, Patricia S. ;
Kosiborod, Mikhail ;
Krumholz, Harlan M. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (21) :2141-2147
[8]   What Have We Learned About Patients With Heart Failure and Preserved Ejection Fraction From DIG-PEF, CHARM-Preserved, and I-PRESERVE? [J].
Campbell, Ross T. ;
Jhund, Pardeep S. ;
Castagno, Davide ;
Hawkins, Nathaniel M. ;
Petrie, Mark C. ;
McMurray, John J. V. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 60 (23) :2349-2356
[9]   Do patients with suspected heart failure and preserved left ventricular systolic function suffer from "diastolic heart failure" or from misdiagnosis? A prospective descriptive study [J].
Caruana, L ;
Petrie, MC ;
Davie, AP ;
McMurray, JJV .
BRITISH MEDICAL JOURNAL, 2000, 321 (7255) :215-218
[10]   National Trends in Heart Failure Hospital Stay Rates, 2001 to 2009 [J].
Chen, Jersey ;
Dharmarajan, Kumar ;
Wang, Yongfei ;
Krumholz, Harlan M. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (10) :1078-1088