Antioxidant Activity of Butane Type Lignans, Secoisolariciresinol, Dihydroguaiaretic Acid, and 7,7′-Oxodihydroguaiaretic Acid

被引：28

作者：

Yamauchi, Satoshi ^{[1
,2
]}

Masuda, Toshiya ^{[3
]}

Sugahara, Takuya ^{[1
,2
]}

Kawaguchi, Yuya ^{[1
]}

Ohuchi, Maya ^{[3
]}

Someya, Tatsushi ^{[3
]}

Akiyama, Jun ^{[3
]}

Tominaga, Shiori ^{[1
]}

Yamawaki, Manami ^{[1
]}

Kishida, Taro ^{[1
,2
]}

Akiyama, Koichi ^{[4
]}

Maruyama, Masafumi ^{[1
]}

机构：

[1] Ehime Univ, Fac Agr, Matsuyama, Ehime 7908566, Japan

[2] S Ehime Fisheries Res Ctr, Ainan, Ehime 7984292, Japan

[3] Univ Tokushima, Fac Integrated Arts & Sci, Tokushima 7708502, Japan

[4] Ehime Univ, Integrated Ctr Sci, Matsuyama, Ehime 7908566, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2008年 / 72卷 / 11期

关键词：

lignan; antioxidant activity; dihydroguaiaretic acid;

D O I：

10.1271/bbb.80461

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The antioxidant activity of butane-type lignans was evaluated. Secoisolariciresinol (SECO) and dihydroguaiaretic acid (DGA) showed higher radical scavenging activity than that of 7,7'-dioxodihydroguaiaretic acid (ODGA). SECO and DGA inhibited the oxidation of unsaturated fatty acid. Both enantiomers of DGA were also lipoxygenase inhibitors, but neither enantiomer of SECO inhibited the lipoxygenase activity.

引用

页码：2981 / 2986

页数：6

共 16 条

[1]

AYRES DC, 1990, LIGNANS

[2] Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs [J].

Blecha, Joseph E. ;

Anderson, Marc O. ;

Chow, Jennifer M. ;

Guevarra, Christle C. ;

Pender, Celia ;

Penaranda, Cristina ;

Zavodovskaya, Marianna ;

Youngren, Jack F. ;

Berkman, Clifford E. .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (14) :4026-4029

[3] ABSOLUTE-CONFIGURATION OF THE LIGNAN OLEIFERINS FROM VIROLA-OLEIFERA [J].

FERNANDES, AMAP ;

BARATA, LES ;

FERRI, PH .

PHYTOCHEMISTRY, 1994, 36 (02) :533-534

[4] Lipoxygenase inhibitory activity of octyl gallate [J].

Ha, TJ ;

Nihei, KI ;

Kubo, I .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (10) :3177-3181

[5] Antioxidant activities of a new lignan and a neolignan from Saururus chinensis [J].

Lee, WS ;

Baek, YI ;

Kim, JR ;

Cho, KH ;

Sok, DE ;

Jeong, TS .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (22) :5623-5628

[6] Antioxidant-related activities of ethanol extracts from edible and medicinal plants cultivated in Okinawa, Japan [J].

Masuda, T ;

Oyama, Y ;

Inaba, Y ;

Toi, Y ;

Arata, T ;

Takeda, Y ;

Nakamoto, K ;

Kuninaga, H ;

Nishizato, S ;

Nonaka, A .

JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI, 2002, 49 (10) :652-661

[7] Nomenclature of lignans and neolignans (IUPAC Recommendations 2000) [J].

Moss, GP .

PURE AND APPLIED CHEMISTRY, 2000, 72 (08) :1493-1523

[8] REGIOSELECTIVE CLEAVAGE OF THE METHYLENEDIOXY GROUP - CONVERSION OF (-)-AUSTROBAILIGNAN-5 TO (-)-DIHYDROGUAIARETIC ACID [J].

RAO, KV ;

CHATTOPADHYAY, SK .

JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (05) :1427-1429

[9] First stereoselective synthesis of meso-secoisolariciresinol and comparison of its biological activity with (+) and (-)-secoisolariciresinol [J].

Sugahara, Takuya ;

Yamauchi, Satoshi ;

Kondo, Ai ;

Ohno, Furni ;

Tominaga, Siori ;

Nakashima, Yuki ;

Kishida, Taro ;

Akiyama, Koichi ;

Maruyama, Masafurni .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2007, 71 (12) :2962-2968

[10] Stereochemical diversity in lignan biosynthesis of Arctium lappa L. [J].

Suzuki, S ;

Umezawa, T ;

Shimada, M .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2002, 66 (06) :1262-1269

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