A power-free microfluidic chip for SNP genotyping using graphene oxide and a DNA intercalating dye

被引：56

作者：

Li, Jing ^{[1
]}

Huang, Yan ^{[1
]}

Wang, Dongfang ^{[1
]}

Song, Bo ^{[1
]}

Li, Zhenhua ^{[1
]}

Song, Shiping ^{[1
]}

Wang, Lihua ^{[1
]}

Jiang, Bowei ^{[1
,2
]}

Zhao, Xingchun ^{[2
]}

Yan, Juan ^{[3
]}

Liu, Rui ^{[3
]}

He, Dannong ^{[3
]}

Fan, Chunhai ^{[1
]}

机构：

[1] Chinese Acad Sci, Phys Biol Lab, Shanghai Inst Appl Phys, Shanghai, Peoples R China

[2] Minist Publ Secur, Inst Forens Sci, Beijing, Peoples R China

[3] Natl Engn Res Ctr Nanotechnol, Shanghai, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 30期

关键词：

MOLECULAR BEACON; POINT MUTATIONS; ADSORPTION; GRAPHITE;

D O I：

10.1039/c3cc40680f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We herein report a power-free microfluidic chip for fluorescent DNA detection with high single-nucleotide polymorphism discrimination, using a DNA intercalator and graphene oxide.

引用

页码：3125 / 3127

页数：3

共 24 条

[1] Functionalization of Graphene: Covalent and Non-Covalent Approaches, Derivatives and Applications [J].

Georgakilas, Vasilios ;

Otyepka, Michal ;

Bourlinos, Athanasios B. ;

Chandra, Vimlesh ;

Kim, Namdong ;

Kemp, K. Christian ;

Hobza, Pavel ;

Zboril, Radek ;

Kim, Kwang S. .

CHEMICAL REVIEWS, 2012, 112 (11) :6156-6214

[2]

He S., 2009, ADV FUNCT MATER, V19, P1

[3] Design of a gold nanoprobe for rapid and portable mercury detection with the naked eye [J].

He, Shijiang ;

Li, Di ;

Zhu, Changfeng ;

Song, Shiping ;

Wang, Lihua ;

Long, Yitao ;

Fan, Chunhai .

CHEMICAL COMMUNICATIONS, 2008, (40) :4885-4887

[4] Molecular Beacon Lighting up on Graphene Oxide [J].

Huang, Po-Jung Jimmy ;

Liu, Juewen .

ANALYTICAL CHEMISTRY, 2012, 84 (09) :4192-4198

[5] Mechanisms for strong adsorption of tetracycline to carbon nanotubes: A comparative study using activated carbon and graphite as adsorbents [J].

Ji, Liangliang ;

Chen, Wei ;

Duan, Lin ;

Zhu, Dongqiang .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2009, 43 (07) :2322-2327

[6] Materials science - Graphene-based materials [J].

Li, Dan ;

Kaner, Richard B. .

SCIENCE, 2008, 320 (5880) :1170-1171

[7] A graphene-enhanced molecular beacon for homogeneous DNA detection [J].

Li, Fan ;

Huang, Yan ;

Yang, Qing ;

Zhong, Zentao ;

Li, Di ;

Wang, Lihua ;

Song, Shiping ;

Fan, Chunhai .

NANOSCALE, 2010, 2 (06) :1021-1026

[8] Capture of double-stranded DNA in stacked-graphene: giving new insight into the graphene/DNA interaction [J].

Liu, Meng ;

Zhao, Huimin ;

Chen, Shuo ;

Yu, Hongtao ;

Quan, Xie .

CHEMICAL COMMUNICATIONS, 2012, 48 (04) :564-566

[9] A Graphene Platform for Sensing Biomolecules [J].

Lu, Chun-Hua ;

Yang, Huang-Hao ;

Zhu, Chun-Ling ;

Chen, Xi ;

Chen, Guo-Nan .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (26) :4785-4787

[10] Detection of point mutations in the HBV polymerase gene using a fluorescence intercalator in reverse micelles [J].

Maruyama, T ;

Takata, T ;

Ichinose, H ;

Kamiya, N ;

Kuma, H ;

Hamasaki, N ;

Morita, H ;

Goto, M .

BIOTECHNOLOGY PROGRESS, 2005, 21 (02) :575-579

← 1 2 3 →