MTOR INHIBITORS PROMOTE AUTOPHAGIC NOT APOPTOTIC CELL DEATH IN PROXIMAL TUBULAR RENAL CELLS, VIA P75NTR ACTIVATION

被引:0
作者
Lupinacci, Simona [1 ]
Toteda, Giuseppina [1 ]
Vizza, Donatella [1 ]
Perri, Anna [1 ]
Gigliotti, Paolo [2 ]
Leone, Francesca [1 ]
Lofaro, Danilo [1 ]
La Russa, Antonella [1 ]
Bonofiglio, Martina [1 ]
Bonofiglio, Renzo [3 ]
机构
[1] Annunziata Hosp, Dept Nephrol Dialysis & Transplantat, Res Ctr Kidney & Transplantat, Cosenza, Italy
[2] Annnunziata Hosp, Dept Nephrol Dialysis & Transplantat, Res Ctr Kidney & Transplantat, Cosenza, Italy
[3] Annunziata Hosp, Nephrol Dialysis & Transplantat, Cosenza, Italy
关键词
D O I
10.1093/ndt/gfv166.6
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
FP018
引用
收藏
页数:1
相关论文
共 50 条
[41]   Nerve growth factor (NGF) exerts its pro-apoptotic effect via the P75NTR receptor in a cell cycle-dependent manner [J].
Bono, F ;
Lamarche, I ;
Bornia, J ;
Savi, P ;
Della Valle, G ;
Herbert, JM .
FEBS LETTERS, 1999, 457 (01) :93-97
[42]   ProNGF induces TNFα-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway [J].
Lebrun-Julien, Frederic ;
Bertrand, Mathieu J. ;
De Backer, Olivier ;
Stellwagen, David ;
Morales, Carlos R. ;
Di Polo, Adriana ;
Barker, Philip A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (08) :3817-3822
[43]   Self-renewal and chemotherapy resistance of p75NTR positive cells in esophageal squamous cell carcinomas [J].
Sheng-Dong Huang ;
Yang Yuan ;
Xiao-Hong Liu ;
De-Jun Gong ;
Chen-Guang Bai ;
Feng Wang ;
Jun-Hui Luo ;
Zhi-Yun Xu .
BMC Cancer, 9
[44]   THE ACTIVATION OF P75NTR RECEPTOR SIGNALING PROMOTES EMT IN ADPKD CELL LINE WT9-12 [J].
Toteda, Giuseppina ;
Lupinacci, Simona ;
Perri, Anna ;
Vizza, Donatella ;
La Russa, Antonella ;
Lofaro, Danilo ;
Gigliotti, Paolo ;
Leone, Francesca ;
Bonofiglio, Renzo .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2020, 35 :325-326
[45]   Expression of p75NTR in a human prostate epithelial tumor cell line reduces nerve growth factor-induced cell growth by activation of programmed cell death [J].
Pflug, B ;
Djakiew, D .
MOLECULAR CARCINOGENESIS, 1998, 23 (02) :106-114
[46]   Nerve growth factor induces photoreceptor cell death via p75NTR. [J].
Srinivasan, B ;
Sheedlo, HJ ;
Al-Ubaidi, MR ;
Roque, RS .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2000, 41 (04) :S403-S403
[47]   Basic fibroblast growth factor-induced cell death is effected through sustained activation of p38MAPK and up-regulation of the death receptor p75NTR [J].
Williamson, AJK ;
Dibling, BC ;
Boyne, JR ;
Selby, P ;
Burchill, SA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (46) :47912-47928
[48]   Self-renewal and chemotherapy resistance of p75NTR positive cells in esophageal squamous cell carcinomas [J].
Huang, Sheng-Dong ;
Yuan, Yang ;
Liu, Xiao-Hong ;
Gong, De-Jun ;
Bai, Chen-Guang ;
Wang, Feng ;
Luo, Jun-Hui ;
Xu, Zhi-Yun .
BMC CANCER, 2009, 9
[49]   Modulating p75NTR protects against ischemic retinopathy via increased vascular homing of mesenchymal stem cells [J].
Elshaer, Sally L. ;
Hill, William Dave ;
Gangaraju, Rajashekhar ;
El-Remessy, Azza B. .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2017, 58 (08)
[50]   Upregulation of p75NTR by Histone Deacetylase Inhibitors Sensitizes Human Neuroblastoma Cells to Targeted Immunotoxin-Induced Apoptosis [J].
Dedoni, Simona ;
Olianas, Alessandra ;
Manconi, Barbara ;
Collu, Maria ;
Tuveri, Barbara ;
Vincis, Maria Elena ;
Olianas, Maria C. ;
Onali, Pierluigi .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (07)