The need for speed

被引：43

作者：

Suhalim, Jeffrey L. ^{[1
]}

Boik, John C. ^{[2
]}

Tromberg, Bruce J. ^{[1
]}

Potma, Eric O. ^{[1
]}

机构：

[1] Univ Calif Irvine, Beckman Laser Inst, Dept Biomed Engn, Irvine, CA 92717 USA

[2] Univ Calif Irvine, Dept Chem, Irvine, CA 92717 USA

来源：

JOURNAL OF BIOPHOTONICS | 2012年 / 5卷 / 5-6期

基金：

美国国家科学基金会;

关键词：

nonlinear microscopy; vibrational imaging; coherent Raman scattering; tissue imaging; IN-VIVO; LABEL-FREE; RAMAN-SPECTROSCOPY; LIVING CELLS; ATHEROSCLEROSIS; MICROSCOPY; MOLECULES; REVEALS; MYELIN; IMPACT;

D O I：

10.1002/jbio.201200002

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

One of the key enabling features of coherent Raman scattering (CRS) techniques is the dramatically improved imaging speed over conventional vibrational imaging methods. It is this enhanced imaging acquisition rate that has guided the field of vibrational microscopy into the territory of real-time imaging of live tissues. In this feature article, we review several aspects of fast vibrational imaging and discuss new applications made possible by the improved CRS imaging capabilities. In addition, we reflect on the current limitations of CRS microscopy and look ahead at several new developments towards real-time, hyperspectral vibrational imaging of biological tissues. (C) 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

引用

页码：387 / 395

页数：9

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