Evaluation of clinical aspects and quality of life as risk factors for depression in patients with epilepsy

被引：21
作者：
Zhao, Ting [1 ]
Sun, Ming-yue [1 ]
Yu, Pei-min [1 ]
Zhu, Guo-xing [1 ]
Tang, Xing-hua [1 ]
Shi, Yun-bo [1 ]
Hong, Zhen [1 ]
机构：
[1] Fudan Univ, Inst Neurol, Huashan Hosp, Shanghai 200040, Peoples R China
来源：
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2012年 / 21卷 / 05期
关键词：
Epilepsy; Depression; Risk factors; Quality of life; 5-HT1A RECEPTOR-BINDING; COMORBID DEPRESSION; PEOPLE; PREVALENCE; DISORDERS; ANXIETY; IMPACT;
D O I：
10.1016/j.seizure.2012.03.006
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The purpose of this study was to investigate clinical aspects and quality of life (QOL) as risk factors for depression in patients with epilepsy. One hundred and forty outpatients with a diagnosis of epilepsy who were attending our epilepsy center participated. Patients anonymously filled out a questionnaire with clinical data related to epilepsy. Depression level was evaluated by the Hamilton Depression Rating Scale-17 (HAMD-17), and quality of life was evaluated by the Quality of Life in Epilepsy-31 (QOLIE-31). Thirty-six patients with epilepsy suffered from depression (25.7%). Complex partial seizures (OR = 0.112) and number of seizure types (OR = 3.773) were found to be clinical risk factors for depression. Low scores for seizure worry (OR = 0.947) and social function (OR = 0.947) on the QOLIE-31 increased the probability of depression in patients with epilepsy. (C) 2012 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：367 / 370
页数：4
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