Evaluation of clinical aspects and quality of life as risk factors for depression in patients with epilepsy

被引:21
作者
Zhao, Ting [1 ]
Sun, Ming-yue [1 ]
Yu, Pei-min [1 ]
Zhu, Guo-xing [1 ]
Tang, Xing-hua [1 ]
Shi, Yun-bo [1 ]
Hong, Zhen [1 ]
机构
[1] Fudan Univ, Inst Neurol, Huashan Hosp, Shanghai 200040, Peoples R China
来源
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2012年 / 21卷 / 05期
关键词
Epilepsy; Depression; Risk factors; Quality of life; 5-HT1A RECEPTOR-BINDING; COMORBID DEPRESSION; PEOPLE; PREVALENCE; DISORDERS; ANXIETY; IMPACT;
D O I
10.1016/j.seizure.2012.03.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The purpose of this study was to investigate clinical aspects and quality of life (QOL) as risk factors for depression in patients with epilepsy. One hundred and forty outpatients with a diagnosis of epilepsy who were attending our epilepsy center participated. Patients anonymously filled out a questionnaire with clinical data related to epilepsy. Depression level was evaluated by the Hamilton Depression Rating Scale-17 (HAMD-17), and quality of life was evaluated by the Quality of Life in Epilepsy-31 (QOLIE-31). Thirty-six patients with epilepsy suffered from depression (25.7%). Complex partial seizures (OR = 0.112) and number of seizure types (OR = 3.773) were found to be clinical risk factors for depression. Low scores for seizure worry (OR = 0.947) and social function (OR = 0.947) on the QOLIE-31 increased the probability of depression in patients with epilepsy. (C) 2012 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:367 / 370
页数:4
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