A Comprehensive Review of Topical Odor-Controlling Treatment Options for Chronic Wounds

被引:48
作者
Akhmetova, Alma [1 ]
Saliev, Timur [2 ]
Allan, Iain U. [3 ]
Illsley, Matthew J. [3 ]
Nurgozhin, Talgat [1 ]
Mikhalovsky, Sergey [3 ,4 ]
机构
[1] Nazarbayev Univ, Natl Lab Astana, Lab Expt & Clin Pharmacol & Pharm, Astana, Kazakhstan
[2] Nazarbayev Univ, Natl Lab Astana, Lab Translat Med & Life Sci Technol, Astana, Kazakhstan
[3] Univ Brighton, Sch Biomat & Biomol Sci, Brighton, E Sussex, England
[4] Nazarbayev Univ, Sch Engn, Astana, Kazakhstan
关键词
Chronic wound; Control; Dressing; Infection; Malodor; Odor; Therapy; RESISTANT STAPHYLOCOCCUS-AUREUS; MANUKA HONEY; ESSENTIAL OILS; BETA-CYCLODEXTRIN; METRONIDAZOLE GEL; GRANULATED SUGAR; PSEUDOMONAS-AERUGINOSA; ANTIBACTERIAL ACTIVITY; POTENTIAL APPLICATIONS; BACTERIAL-RESISTANCE;
D O I
10.1097/WON.0000000000000273
中图分类号
R47 [护理学];
学科分类号
1011 ;
摘要
The process of wound healing is often accompanied by bacterial infection or critical colonization, resulting in protracted inflammation, delayed reepithelization, and production of pungent odors. The malodor produced by these wounds may lower health-related quality of life and produce psychological discomfort and social isolation. Current management focuses on reducing bacterial activity within the wound site and absorbing malodorous gases. For example, charcoal-based materials have been incorporated into dressing for direct adsorption of the responsible gases. In addition, multiple topical agents, including silver, iodine, honey, sugar, and essential oils, have been suggested for incorporation into dressings in an attempt to control the underlying bacterial infection. This review describes options for controlling malodor in chronic wounds, the benefits and drawbacks of each topical agent, and their mode of action. We also discuss the use of subjective odor evaluation techniques to assess the efficacy of odor-controlling therapies. The perspectives of employing novel biomaterials and technologies for wound odor management are also presented.
引用
收藏
页码:598 / 609
页数:12
相关论文
共 143 条
[1]  
Andjarwati R, 2010, J WOUND OSTOMY CONT, V37, pS4
[2]  
[Anonymous], 2012, APP 5 DERB WOUND CAR
[3]  
Ashour HM, 2008, FASEB J, V22
[4]   Development of conducting polymer sensor arrays for wound monitoring [J].
Bailey, Arthur L. R. S. ;
Pisanelli, Anna Maria ;
Persaud, Krishna C. .
SENSORS AND ACTUATORS B-CHEMICAL, 2008, 131 (01) :5-9
[5]  
Bale Sue, 2004, Br J Nurs, V13, pS4
[6]  
Bansal R.C., 2005, ACTIVATED CARBON ADS, P1, DOI DOI 10.1201/9781420028812
[7]  
Beadling L, 1997, Todays Surg Nurse, V19, P28
[8]  
Biswas Atanu, 2010, J Diabetes Sci Technol, V4, P1139
[9]   A DOUBLE-BLIND-STUDY OF THE EFFICACY OF METRONIDAZOLE GEL IN THE TREATMENT OF MALODOROUS FUNGATING TUMORS [J].
BOWER, M ;
STEIN, R ;
EVANS, TRJ ;
HEDLEY, A ;
PERT, P ;
COOMBES, RC .
EUROPEAN JOURNAL OF CANCER, 1992, 28A (4-5) :888-889
[10]  
Bowler P G, 1999, J Wound Care, V8, P216