The Active Site Dynamics of Computationally Designed Enzymes

被引:0
|
作者
Kiss, Gert [1 ]
Houk, Kendall [2 ]
Baker, David [3 ]
Pande, Vijay [1 ]
机构
[1] Stanford Univ, Stanford, CA 94305 USA
[2] Univ Calif Los Angeles, Los Angeles, CA USA
[3] Univ Washington, Seattle, WA 98195 USA
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:182 / 182
页数:1
相关论文
共 50 条
  • [21] Allosteric Regulation of Protein Kinase Enzymes via an Electrostatic Switch that Modulates Active Site Dynamics
    Young, Matthew A.
    Jacobsen, Douglas M.
    Bao, Zhao-Qin
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 651A - 651A
  • [22] Photochemical processes in flavo-enzymes as a probe for active site dynamics: TrmFO of Thermus thermophilus
    Zhuang, Bo
    Nag, Lipsa
    Sournia, Pierre
    Croitoru, Anastasia
    Ramodiharilafy, Rivo
    Lambry, Jean-Christophe
    Myllykallio, Hannu
    Aleksandrov, Alexey
    Liebl, Ursula
    Vos, Marten H.
    PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2021, 20 (05) : 663 - 670
  • [23] Photochemical processes in flavo-enzymes as a probe for active site dynamics: TrmFO of Thermus thermophilus
    Bo Zhuang
    Lipsa Nag
    Pierre Sournia
    Anastasia Croitoru
    Rivo Ramodiharilafy
    Jean-Christophe Lambry
    Hannu Myllykallio
    Alexey Aleksandrov
    Ursula Liebl
    Marten H. Vos
    Photochemical & Photobiological Sciences, 2021, 20 : 663 - 670
  • [24] Allosteric regulation of protein kinase enzymes via an electrostatic switch that modulates active site dynamics
    Young, Matthew A.
    Jacobsen, Douoglas M.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 248
  • [25] Ornithine transcarbamylase has a spatially extended active site as computationally predicted
    Ngu, Lisa
    Ramos, Kevin
    DeLateur, Nicholas
    Beuning, Penny
    Ondrechen, Mary Jo
    PROTEIN SCIENCE, 2015, 24 : 65 - 65
  • [26] Validation of active-site mapping of enzymes
    Kuster, Daniel J.
    Marshall, Garland R.
    UNDERSTANDING BIOLOGY USING PEPTIDES, 2006, : 720 - +
  • [27] Bioinspired catalysts: Mimicking the active site of enzymes
    Nothling, Mitchell
    Espinosa, Andrea
    Xiao, Zeyun
    Hawker, Craig
    Connal, Luke
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [28] IMMOBILIZATION OF ENZYMES MASKS THEIR ACTIVE-SITE
    KUMAKURA, M
    KAETSU, I
    BIOSCIENCE REPORTS, 1984, 4 (03) : 181 - 187
  • [29] ACTIVE SITE EVOLUTION IN BIOMASS DEGRADING ENZYMES
    Frandsen, Kristian E. H.
    Tandrup, Tobias
    Poulsen, Jens-Christian N.
    Mazurkewich, Scott
    Huang, Qian
    Labourel, Aurore
    Garcia-Santamarina, Sarela
    Baath, Arnling Jenny
    Tovborg, Morten
    Berrin, Jean-Guy
    Thiele, Dennis J.
    Larsbrink Johan
    Johansen, Katja S.
    Lo Leggio, Leila
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2019, 75 : E124 - E124
  • [30] The evolution of multiple active site configurations in a designed enzyme
    Nan-Sook Hong
    Dušan Petrović
    Richmond Lee
    Ganna Gryn’ova
    Miha Purg
    Jake Saunders
    Paul Bauer
    Paul D. Carr
    Ching-Yeh Lin
    Peter D. Mabbitt
    William Zhang
    Timothy Altamore
    Chris Easton
    Michelle L. Coote
    Shina C. L. Kamerlin
    Colin J. Jackson
    Nature Communications, 9