Viral Related Tools against SARS-CoV-2

被引：3

作者：

Fernandez-Garcia, Laura ^{[1
,2
]}

Pacios, Olga ^{[1
,2
]}

Gonzalez-Bardanca, Monica ^{[1
,2
]}

Blasco, Lucia ^{[1
,2
]}

Bleriot, Ines ^{[1
,2
]}

Ambroa, Anton ^{[1
,2
]}

Lopez, Maria ^{[1
,2
]}

Bou, German ^{[1
,2
,3
]}

Tomas, Maria ^{[1
,2
,3
]}

机构：

[1] Univ A Coruna UDC, Dept Microbiol, Res Inst Biomed A Coruna INIBIC, Hosp A Coruna CHUAC, La Coruna 15006, Spain

[2] Spanish Soc Infect Dis & Clin Microbiol SEIMC, Study Grp Mech Act & Resistance Antimicrobials GE, Madrid 28003, Spain

[3] Spanish Network Res Infect Dis REIPI, Seville 41071, Spain

来源：

VIRUSES-BASEL | 2020年 / 12卷 / 10期

关键词：

SARS-CoV-2; COVID-19; phages; CRISPR; viruses; prevention; diagnosis; treatment; PHAGE DISPLAY; NEUTRALIZING ANTIBODY; FILAMENTOUS PHAGE; GENE-THERAPY; CRISPR-CAS; VIRUS; CORONAVIRUS; SELECTION; IMMUNOGENICITY; IDENTIFICATION;

D O I：

10.3390/v12101172

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

At the end of 2019, a new disease appeared and spread all over the world, the COVID-19, produced by the coronavirus SARS-CoV-2. As a consequence of this worldwide health crisis, the scientific community began to redirect their knowledge and resources to fight against it. Here we summarize the recent research on viruses employed as therapy and diagnostic of COVID-19: (i) viral-vector vaccines both in clinical trials and pre-clinical phases; (ii) the use of bacteriophages to find antibodies specific to this virus and some studies of how to use the bacteriophages themselves as a treatment against viral diseases; and finally, (iii) the use of CRISPR-Cas technology both to obtain a fast precise diagnose of the patient and also the possible use of this technology as a cure.

引用

页数：19

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