Evolution of Transcatheter Aortic Valve Replacement

被引：55

作者：

Bourantas, Christos V. ^{[1
]}

Serruys, Patrick W. ^{[1
,2
]}

机构：

[1] Erasmus MC, Dept Intervent Cardiol, Thoraxctr, NL-3015 CE Rotterdam, Netherlands

[2] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, Int Ctr Circulatory Hlth, London, England

来源：

CIRCULATION RESEARCH | 2014年 / 114卷 / 06期

关键词：

aortic valve stenosis; prognosis; COREVALVE REVALVING SYSTEM; PERMANENT PACEMAKER IMPLANTATION; BUNDLE-BRANCH BLOCK; HIGH-RISK PATIENTS; EDWARDS SAPIEN VALVE; MULTIDETECTOR COMPUTED-TOMOGRAPHY; BIOPROSTHETIC HEART-VALVES; EMBOLIC DEFLECTION DEVICE; OUTCOME SOURCE REGISTRY; PREDICTIVE FACTORS;

D O I：

10.1161/CIRCRESAHA.114.302292

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Transcatheter aortic valve replacement emerged approximate to 20 years ago and changed the landscape of structural interventional cardiology. The first experiments in animal models provided proofs of the concept and the substrate for the first percutaneous valve implantation in patients. The initial promising results in a clinical setting drew the attention of the industry and of the scientific community, and an effort was made for the past 12 years to address the limitations of the technology, facilitate the procedure, minimize the risk of complications, and broaden the applications of transcatheter aortic valve replacement. This article reviews the evolution of transcatheter aortic valve replacement, presents the first steps in this field, cites the evidence from registries and clinical trials, highlights the limitations of this treatment, and discusses the future perspectives and the developments proposed to address the current pitfalls.

引用

页码：1037 / 1051

页数：15

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