Interfacial properties of morpholine-2,5-dione-based oligodepsipeptides and multiblock copolymers

被引：2

作者：

Machatschek, Rainhard ^{[1
,2
]}

Schoene, Anne-Christin ^{[1
,2
]}

Raschdorf, Elisa ^{[3
]}

Ihlenburg, Ramona B. J. ^{[1
,2
,3
]}

Schulz, Burkhard ^{[1
,2
,3
]}

Lendlein, Andreas ^{[1
,2
,3
]}

机构：

[1] Helmholtz Zentrum Geesthacht, Inst Biomat Sci, Kantstr 55, D-14513 Teltow, Germany

[2] Berlin Brandenburg Ctr Regenerat Therapies, Kantstr 55, D-14513 Teltow, Germany

[3] Univ Potsdam, Inst Chem, Karl Liebknecht Str 24-25, D-14469 Potsdam, Germany

来源：

MRS COMMUNICATIONS | 2019年 / 9卷 / 01期

关键词：

BLOCK-COPOLYMER; ENZYMATIC DEGRADATION; POLY(ESTER AMIDE)S; CONTROLLED-RELEASE; FILMS; NANOCARRIERS;

D O I：

10.1557/mrc.2019.21

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Oligodepsipeptides (ODPs) with alternating amide and ester bonds prepared by ring-opening polymerization of morpholine-2,5-dione derivatives are promising matrices for drug delivery systems and building blocks for multifunctional biomaterials. Here, we elucidate the behavior of three telechelic ODPs and one multiblock copolymer containing ODP blocks at the air-water interface. Surprisingly, whereas the oligomers and multiblock copolymers crystallize in bulk, no crystallization is observed at the air-water interface. Furthermore, polarization modulation infrared reflection absorption spectroscopy is used to elucidate hydrogen bonding and secondary structures in ODP monolayers. The results will direct the development of the next ODP-based biomaterial generation with tailored properties for highly sophisticated applications.

引用

页码：170 / 180

页数：11

共 50 条

[1] Interfacial properties of morpholine-2,5-dione-based oligodepsipeptides and multiblock copolymers
Rainhard Machatschek
Anne-Christin Schöne
Elisa Raschdorf
Ramona B. J. Uilenburg
Burkhard Schulz
Andreas Lendlein
MRS Communications, 2019, 9 : 170 - 180
[2] Hexyl-modified morpholine-2,5-dione-based oligodepsipeptides with relatively low glass transition temperature
Peng, Xingzhou
Behl, Marc
Zhang, Pengfei
Mazurek-Budzynska, Magdalena
Razzaq, Muhammad Yasar
Lendlein, Andreas
POLYMER, 2016, 105 : 318 - 326
[3] Morpholine-2,5-dione
Martínez-Palau, M
Urpí, L
Solans, X
Puiggalí, J
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2006, 62 (05): : O262 - O264
[4] Simple and Rapid Mechanochemical Synthesis of Lactide and 3S-(Isobutyl)morpholine-2,5-dione-Based Random Copolymers Using DBU and Thiourea
Burton, Tobias F.
Pinaud, Julien
Petry, Nicolas
Lamaty, Frederic
Giani, Olivia
ACS MACRO LETTERS, 2021, 10 (12) : 1454 - 1459
[5] Synthesis of Morpholine-2,5-dione Monomers for the Preparation of Polydepsipeptides
Abdelmelek, Mena
Mary Nguyen
Bradford, Valerie
Iverson, Brent
Suggs, Laura
BIOMATERIALS, 2010, 1054 : 185 - 196
[6] Biodegradable Multiblock Copolymers Based on Oligodepsipeptides with Shape-Memory Properties
Feng, Yakai
Behl, Marc
Kelch, Steffen
Lendlein, Andreas
MACROMOLECULAR BIOSCIENCE, 2009, 9 (01) : 45 - 54
[7] COPOLYMERIZATION OF EPSILON-CAPROLACTONE AND MORPHOLINE-2,5-DIONE DERIVATIVES
VELD, PJA
YE, WP
KLAP, R
DIJKSTRA, PJ
FEIJEN, J
MAKROMOLEKULARE CHEMIE-MACROMOLECULAR CHEMISTRY AND PHYSICS, 1992, 193 (08): : 1927 - 1942
[8] Cyclooctyne End-Functionalized Poly(morpholine-2,5-dione)s
Schreiber, Johanna
Goeppert, Natalie E.
Stafast, Leanne M.
Weber, Christine
Schubert, Ulrich S.
MACROMOLECULAR RAPID COMMUNICATIONS, 2025, 46 (03)
[9] Synthesis of morpholine-2,5-dione derivative copolymer and its degradation in vitro
Zhao Y.
Cheng S.
Chen J.
Frontiers of Materials Science in China, 2007, 1 (2): : 151 - 157
[10] SYNTHESIS OF ALTERNATING POLYDEPSIPEPTIDES BY RING-OPENING POLYMERIZATION OF MORPHOLINE-2,5-DIONE DERIVATIVES
TVELD, PJA
DIJKSTRA, PJ
VANLOCHEM, JH
FEIJEN, J
MAKROMOLEKULARE CHEMIE-MACROMOLECULAR CHEMISTRY AND PHYSICS, 1990, 191 (08): : 1813 - 1825

← 1 2 3 4 5 →