Genetic variation affects de novo translocation frequency

被引：60

作者：

Kato, T

Inagaki, H

Yamada, K

Kogo, H

Ohye, T

Kowa, H

Nagaoka, K

Taniguchi, M

Emanuel, BS

Kurahashi, H ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Inst Comprehens Med Sci, Div Mol Genet, Philadelphia, PA 19104 USA

[2] Univ Penn, Sch Med, Dept Pediat, Philadelphia, PA 19104 USA

来源：

SCIENCE | 2006年 / 311卷 / 5763期

关键词：

D O I：

10.1126/science.1121452

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.

引用

页码：971 / 971

页数：1

共 9 条

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