Nephrogenic Systemic Fibrosis

被引：87

作者：

Kaewlai, Rathachai ^{[2
,3
]}

Abujudeh, Hani ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02114 USA

[2] Ramathibodi Hosp, Div Emergency Radiol, Dept Radiol, Bangkok, Thailand

[3] Mahidol Univ, Bangkok 10700, Thailand

来源：

AMERICAN JOURNAL OF ROENTGENOLOGY | 2012年 / 199卷 / 01期

关键词：

gadolinium-based contrast agents; kidney function; MRI; nephrogenic systemic fibrosis (NSF); IMAGING CONTRAST AGENTS; RENAL-FAILURE; GADOLINIUM; DERMOPATHY; RISK; SKIN; GADODIAMIDE; GADOPENTETATE; PREVALENCE; DEPOSITION;

D O I：

10.2214/AJR.11.8144

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

OBJECTIVE. The purpose of this article is to discuss nephrogenic systemic fibrosis (NSF) in detail regarding its history, possible pathophysiology, clinical and pathologic presentations, diagnosis, and implications for the radiology community. CONCLUSION. NSF is a potentially lethal disorder that occurs in patients with reduced kidney function. Current evidence suggests a strong association with gadolinium-based contrast agents-mostly used in MRI-in this patient group. This has urged the radiology community to emphasize careful screening for the presence of renal dysfunction among patients for whom gadolinium-enhanced MRI is contemplated. Appropriate selection of gadolinium-based contrast agent type, avoidance of nonstandard dosage, patient education, and informed consent have been recommended by authorities.

引用

页码：W17 / W23

页数：7

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