Metabolic syndrome in young people

被引:60
作者
Poyrazoglu, Sukran [1 ]
Bas, Firdevs [1 ]
Darendeliler, Feyza [1 ]
机构
[1] Istanbul Univ, Istanbul Fac Med, Dept Pediat, Pediat Endocrinol Unit, Istanbul, Turkey
关键词
insulin-resistance; metabolic syndrome; obesity; 3RD NATIONAL-HEALTH; FATTY LIVER-DISEASE; BODY-MASS INDEX; INSULIN-RESISTANCE; OBESE CHILDREN; WEIGHT-GAIN; PREMATURE ADRENARCHE; CARDIOVASCULAR RISK; GLUCOSE-TOLERANCE; MATERNAL OBESITY;
D O I
10.1097/01.med.0000436414.90240.2c
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of reviewThe prevalence of obesity is on the increase, and consequently metabolic syndrome is also becoming a serious health problem in children and adolescents all over the world. This review attempts to summarize the recent literature on metabolic syndrome in children and adolescents.Recent findingsTo date, a standard definition of metabolic syndrome for the pediatric population is not available. Recently, the International Diabetes Federation has proposed a new set of criteria to define metabolic syndrome in children and adolescents aged 6-16 years. The relationships between obesity, insulin resistance and metabolic syndrome may be explained by the pattern of lipid partitioning. Fatty liver plays a central role in the insulin-resistant state in obese adolescents. Although insulin resistance has been proposed as the central factor leading to the abnormalities observed in metabolic syndrome, most definitions of metabolic syndrome use impaired fasting glucose as a marker. Nutrition impairment during both prenatal and early postnatal life can cause metabolic disturbances leading to insulin-resistance, type 2 diabetes, hypertension and cardiovascular disease.SummaryMetabolic syndrome prevalence in children and adolescents is on the increase. Therefore, the emphasis in all studies and programs related to metabolic syndrome should be focused on prevention, early detection of metabolic risk factors and interventions that will have a significant impact on future adult health.
引用
收藏
页码:56 / 63
页数:8
相关论文
共 50 条
[41]   The dietary inflammatory index and insulin resistance or metabolic syndrome in young adults [J].
Carvalho, Carolina A. ;
Silva, Antonio Augusto M. ;
Assuncao, Maria Cecilia F. ;
Fonseca, Poliana Cristina A. ;
Barbieri, Marco Antonio ;
Bettiol, Heloisa ;
Shivappa, Nitin ;
Hebert, James R. .
NUTRITION, 2019, 58 :187-193
[42]   Peripheral Lymphocytes, Obesity, and Metabolic Syndrome in Young Adults: An Immunometabolism Study [J].
Paulina Rodriguez, Carmen ;
Cristina Gonzalez, Maria ;
Aguilar-Salinas, Carlos A. ;
Najera-Medina, Oralia .
METABOLIC SYNDROME AND RELATED DISORDERS, 2018, 16 (07) :342-349
[43]   Associations Among Depression, Obesity, and Metabolic Syndrome in Young Adult Females [J].
Lin, Kuan Pin ;
Liang, Tien Li ;
Liao, I. Chen ;
Tsay, Shiow Luan .
BIOLOGICAL RESEARCH FOR NURSING, 2014, 16 (03) :327-334
[44]   The Role of Different Methods in Defining Cardiometabolic Risk and Metabolic Syndrome in Women with Polycystic Ovary Syndrome [J].
Bicer, Nihan Cakir ;
Ermis, Asime Aleyna ;
Bas, Dilsat .
LIFE-BASEL, 2023, 13 (10)
[45]   The metabolic syndrome in young Korean women with polycystic ovary syndrome [J].
Park, Hwi Ra ;
Choi, Youngju ;
Lee, Hye-Jin ;
Oh, Jee-Young ;
Hong, Young Sun ;
Sung, Yeon-Ah .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2007, 77 :S243-S246
[46]   Metabolic syndrome in young Czech women with polycystic ovary syndrome [J].
Vrbíková, J ;
Vondra, K ;
Cibula, D ;
Dvoráková, K ;
Stanická, S ;
Srámková, D ;
Sindelka, G ;
Hill, M ;
Bendlová, B ;
Skrha, J .
HUMAN REPRODUCTION, 2005, 20 (12) :3328-3332
[47]   Genetic factors associated with risk of metabolic syndrome and hepatocellular carcinoma [J].
Tang, Ranran ;
Liu, Heng ;
Yuan, Yingdi ;
Xie, Kaipeng ;
Xu, Pengfei ;
Liu, Xiaoyun ;
Wen, Juan .
ONCOTARGET, 2017, 8 (21) :35403-35411
[48]   The Causal Role of Ectopic Fat Deposition in the Pathogenesis of Metabolic Syndrome [J].
Janssen, Joseph A. M. J. L. .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (24)
[49]   Prediction of developing metabolic syndrome after gestational diabetes mellitus [J].
Akinci, Baris ;
Celtik, Aygul ;
Yener, Serkan ;
Yesil, Sena .
FERTILITY AND STERILITY, 2010, 93 (04) :1248-1254
[50]   Prevalence of metabolic syndrome in young men in Japan [J].
Saito, Ikuo ;
Mori, Masaaki ;
Shibata, Hirotaka ;
Hirose, Hiroshi ;
Tsujioka, Minako ;
Kawabe, Hiroshi .
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 2007, 14 (01) :27-30