Mucor circinelloides as a Cause of Invasive Maxillofacial Zygomycosis: an Emerging Dimorphic Pathogen with Reduced Susceptibility to Posaconazole

被引：28

作者：

Khan, Zia U. ^{[1
]}

Ahmad, Suhail ^{[1
]}

Brazda, Arnost ^{[2
]}

Chandy, Rachel ^{[1
]}

机构：

[1] Kuwait Univ, Fac Med, Dept Microbiol, Safat 13110, Kuwait

[2] Farwanya Hosp, Minist Hlth, Dept Maxillofacial Surg, Farwanya, Kuwait

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2009年 / 47卷 / 04期

关键词：

IN-VITRO SUSCEPTIBILITIES; BREAKTHROUGH ZYGOMYCOSIS; SALVAGE THERAPY; AMPHOTERICIN-B; VORICONAZOLE; IDENTIFICATION; MUCORMYCOSIS; CULTURE; DNA; GALACTOMANNAN;

D O I：

10.1128/JCM.02030-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A case of maxillofacial zygomycosis caused by Mucor circinelloides, identified by phenotypic and molecular methods and treated successfully with liposomal amphotericin B (AmBisome) and surgical debridement, is described. The isolate was resistant to posaconazole. This report underscores the importance of prior susceptibility testing of zygomycetes to guide therapy with the most effective antifungal agent for an improved prognosis.

引用

页码：1244 / 1248

页数：5

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