4-acyl-2H-thiopyran-3,5(4H,6H)-diones:: Synthesis, oxidation, and reaction with amines

被引：4

作者：

Zheldakova, TA ^{[1
]}

Budnikova, MV ^{[1
]}

Rubinova, IL ^{[1
]}

Rubinov, DB ^{[1
]}

机构：

[1] Natl Acad Sci Belarus, Inst Bioorgan Chem, Minsk 220141, BELARUS

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 39卷 / 12期

关键词：

D O I：

10.1023/B:RUJO.0000019742.81245.f7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acylation of 2H-thiopyran-3,5(4H,6H)-dione and 2-methyl-2H-thiopyran-3,5(4H,6H)-dione with acetyl chloride or propionyl chloride afforded the corresponding 4-acyl-2H-thiopyran-3,5(4H,6H)-diones. Oxidation of 4-acetyl-2H-thiopyran-3,5(4H,6H)-dione with m-chloroperoxybenzoic acid gave 4-acetyl-2H-thiopyran-3,5(4H,6H)-dione I-oxide. 4-Acyl-2H-thiopyran-3,5(4H,6H)-diones and 4-acetyl-2H-thiopyran3,5(4H,6H)-dione I-oxide reacted with pyrrolidine, allylamine, and p-anisidine, resulting in formation of the corresponding 4-aminomethylene derivatives.

引用

页码：1772 / 1776

页数：5

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