Zinc-Catalyzed Synthesis of Functionalized Furans and Triarylmethanes from Enynones and Alcohols or Azoles: Dual X-H Bond Activation by Zinc

被引：119

作者：

Gonzalez, Jesus ^{[1
,2
]}

Gonzalez, Javier ^{[1
,2
]}

Perez-Calleja, Carmela ^{[1
,2
]}

Lopez, Luis A. ^{[1
,2
]}

Vicente, Ruben ^{[1
,2
]}

机构：

[1] Univ Oviedo, Dept Quim Organ & Inorgan, Oviedo 33007, Spain

[2] Univ Oviedo, Inst Univ Quim Organomet Enrique Moles, Oviedo 33007, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 22期

关键词：

alkynes; carbenes; cyclization; furans; zinc; SUBSTITUTED FURANS; ALLYLIC ALKYLATION; ALPHA-OLIGOFURANS; TERMINAL ALKYNES; EFFICIENT; IRON; ARYLATION; ENZYMES; ANALOGS; AMINES;

D O I：

10.1002/anie.201301625

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ba'zinc'ga! A zinc-catalyzed sequence involving a cyclization with a subsequent C-O, C-N, or C-C bond formation enables the preparation of a variety of valuable furfuryl ethers (with alcohols) and unsymmetrically substituted triarylmethane derivatives (with azoles or arenes). ZnCl2 serves as the catalyst. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：5853 / 5857

页数：5

共 60 条

[31] THE CATALYTIC CARBOXYESTER HYDROLYSIS BY A NEW ZINC(II) COMPLEX WITH AN ALCOHOL-PENDANT CYCLEN (1-(2-HYDROXYETHYL)-1,4,7,10-TETRAAZACYCLODODECANE) - A NOVEL MODEL FOR INDIRECT ACTIVATION OF THE SERINE NUCLEOPHILE BY ZINC(II) IN ZINC ENZYMES [J].