Synthesis and antioxidant activity of a novel class of fluorescein-based β-C-glycosides

被引：11

作者：

Rajasekar, Mani ^{[1
]}

Das, Thangamuthu Mohan ^{[1
,2
]}

机构：

[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India

[2] CUTN, Sch Basic & Appl Sci, Dept Chem, Thiruvarur 610004, India

来源：

CARBOHYDRATE RESEARCH | 2013年 / 379卷

关键词：

Fluorescein derivatives; beta-C-glycosides; Aldol condensation; Antioxidant activity; CONDENSATION; ANALOG;

D O I：

10.1016/j.carres.2013.06.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of fluorescein-based beta-C-glycosyl ketones were synthesized through aldol condensation of beta-C-glycosyl ketones with fluorescein monoaldehyde under ambient reaction conditions in good yields. Formation of the expected product has been confirmed through different spectral techniques. Fluorescein-based beta-C-glycosides show moderate anti-oxidant activities with maximum inhibitory activity of 60%. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：38 / 42

页数：5

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