Phosphotyrosine-binding domains in signal transduction

被引：279
作者：
Yaffe, MB [1 ]
机构：
[1] MIT, Ctr Canc Res, Dept Biol, Cambridge, MA 02139 USA
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2002年 / 3卷 / 03期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1038/nrm759
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Protein phosphorylation provides molecular control of complex physiological events within cells. In many cases, phosphorylation on specific amino acids directly controls the assembly of multiprotein complexes by recruiting phospho-specific binding modules. Here, the function, structure and cell biology of phosphotyrosine-binding domains is discussed.
引用
收藏
页码：177 / 186
页数：10
相关论文
共 148 条
  • [11] Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK
    Cleghon, V
    Gayko, U
    Copeland, TD
    Perkins, LA
    Perrimon, N
    Morrison, DK
    [J]. GENES & DEVELOPMENT, 1996, 10 (05) : 566 - 577
  • [12] Opposing actions of CSW and RasGAP modulate the strength of torso RTK signaling in the Drosophila terminal pathway
    Cleghon, V
    Feldmann, P
    Ghiglione, C
    Copeland, TD
    Perrimon, N
    Hughes, DA
    Morrison, DK
    [J]. MOLECULAR CELL, 1998, 2 (06) : 719 - 727
  • [13] Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
    Coffey, AJ
    Brooksbank, RA
    Brandau, O
    Oohashi, T
    Howell, GR
    Bye, JM
    Cahn, AP
    Durham, J
    Heath, P
    Wray, P
    Pavitt, R
    Wilkinson, J
    Leversha, M
    Huckle, E
    Shaw-Smith, CJ
    Dunham, A
    Rhodes, S
    Schuster, V
    Porta, G
    Yin, L
    Serafini, P
    Sylla, B
    Zollo, M
    Franco, B
    Bolino, A
    Seri, M
    Lanyi, A
    Davis, JR
    Webster, D
    Harris, A
    Lenoir, G
    St Basile, GD
    Jones, A
    Behloradsky, BH
    Achatz, H
    Murken, J
    Fassler, R
    Sumegi, J
    Romeo, G
    Vaudin, M
    Ross, MT
    Meindl, A
    Bentley, DR
    [J]. NATURE GENETICS, 1998, 20 (02) : 129 - 135
  • [14] N-TERMINAL DELETIONS IN ROUS-SARCOMA VIRUS P60SRC - EFFECTS ON TYROSINE KINASE AND BIOLOGICAL-ACTIVITIES AND ON RECOMBINATION IN TISSUE-CULTURE WITH THE CELLULAR SRC GENE
    CROSS, FR
    GARBER, EA
    HANAFUSA, H
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1985, 5 (10) : 2789 - 2795
  • [15] Multiple ErbB-2/Neu phosphorylation sites mediate transformation through distinct effector proteins
    Dankort, D
    Jeyabalan, N
    Jones, N
    Dumont, DJ
    Muller, WJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (42) : 38921 - 38928
  • [16] A CONSERVED DOMAIN REGULATES INTERACTIONS OF THE V-FPS PROTEIN-TYROSINE KINASE WITH THE HOST-CELL
    DECLUE, JE
    SADOWSKI, I
    MARTIN, GS
    PAWSON, T
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (24) : 9064 - 9068
  • [17] Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors
    Dhalluin, C
    Yan, KS
    Plotnikova, O
    Lee, KW
    Zeng, L
    Kuti, M
    Mujtaba, S
    Goldfarb, MM
    Zhou, MM
    [J]. MOLECULAR CELL, 2000, 6 (04) : 921 - 929
  • [18] The mammalian Numb phosphotyrosine-binding domain - Characterization of binding specificity and identification of a novel PDZ domain-containing Numb binding protein, LNX
    Dho, SE
    Jacob, S
    Wolting, CD
    French, MB
    Rohrschneider, LR
    McGlade, CJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (15) : 9179 - 9187
  • [19] RECOGNITION OF A HIGH-AFFINITY PHOSPHOTYROSYL PEPTIDE BY THE SRC HOMOLOGY-2 DOMAIN OF P56(LCK)
    ECK, MJ
    SHOELSON, SE
    HARRISON, SC
    [J]. NATURE, 1993, 362 (6415) : 87 - 91
  • [20] Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor
    Eck, MJ
    DhePaganon, S
    Trub, T
    Nolte, RT
    Shoelson, SE
    [J]. CELL, 1996, 85 (05) : 695 - 705
12345678910