Phosphotyrosine-binding domains in signal transduction

被引：279
作者：
Yaffe, MB [1 ]
机构：
[1] MIT, Ctr Canc Res, Dept Biol, Cambridge, MA 02139 USA
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2002年 / 3卷 / 03期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1038/nrm759
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Protein phosphorylation provides molecular control of complex physiological events within cells. In many cases, phosphorylation on specific amino acids directly controls the assembly of multiprotein complexes by recruiting phospho-specific binding modules. Here, the function, structure and cell biology of phosphotyrosine-binding domains is discussed.
引用
收藏
页码：177 / 186
页数：10
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