Cardiovascular diseases: Interplay of epigenetics

被引：10
作者：
Ahuja, Yog R. [1 ]
Sharma, Sanjeev [2 ]
Mohan, Vasavi [1 ,3 ]
机构：
[1] Vasavi Med & Res Ctr, Dept Genet & Mol Med, 6-1-91 Vasavi Hosp, Hyderabad, Andhra Pradesh, India
[2] Apollo Hosp, Dept Clin Pharmacol, Jubilee Hills, Hyderabad, Andhra Pradesh, India
[3] Hansgene Canc Fdn, Res Unit, Hyderabad, Andhra Pradesh, India
来源：
CLINICAL AND EXPERIMENTAL HYPERTENSION | 2017年 / 39卷 / 01期
关键词：
Cardiovascular disease; epigenetic; factors; therapeutic; CARDIAC-HYPERTROPHY; DNA METHYLATION; MICRORNAS; CARDIOMYOCYTES; HYPERTENSION; EXPRESSION; RNA;
D O I：
10.1080/10641963.2016.1210627
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Several association studies have been carried out to elucidate the role of genetic variants in cardiovascular diseases (CVDs), while studies on the epigenome regulating gene expression changes are helping to understand the development of disease and factors promoting such changes. This review summarizes the different epigenetic aspects involved in cardiac development and disease along with current therapeutic interventions.
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页码：1 / 7
页数：7
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