Cardiovascular diseases: Interplay of epigenetics

被引:10
|
作者
Ahuja, Yog R. [1 ]
Sharma, Sanjeev [2 ]
Mohan, Vasavi [1 ,3 ]
机构
[1] Vasavi Med & Res Ctr, Dept Genet & Mol Med, 6-1-91 Vasavi Hosp, Hyderabad, Andhra Pradesh, India
[2] Apollo Hosp, Dept Clin Pharmacol, Jubilee Hills, Hyderabad, Andhra Pradesh, India
[3] Hansgene Canc Fdn, Res Unit, Hyderabad, Andhra Pradesh, India
关键词
Cardiovascular disease; epigenetic; factors; therapeutic; CARDIAC-HYPERTROPHY; DNA METHYLATION; MICRORNAS; CARDIOMYOCYTES; HYPERTENSION; EXPRESSION; RNA;
D O I
10.1080/10641963.2016.1210627
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Several association studies have been carried out to elucidate the role of genetic variants in cardiovascular diseases (CVDs), while studies on the epigenome regulating gene expression changes are helping to understand the development of disease and factors promoting such changes. This review summarizes the different epigenetic aspects involved in cardiac development and disease along with current therapeutic interventions.
引用
收藏
页码:1 / 7
页数:7
相关论文
共 50 条
  • [1] Studying Epigenetics of Cardiovascular Diseases on Chip Guide
    Alghamdi, Bandar Ali
    Aljohani, Intisar Mahmoud
    Alotaibi, Bandar Ghazi
    Ahmed, Muhammad
    Almazmomi, Kholod Abduallah
    Aloufi, Salman
    Alshamrani, Jowhra
    CARDIOGENETICS, 2022, 12 (03) : 218 - 234
  • [2] An Introduction to Epigenetics in Cardiovascular Development, Disease, and Sexualization
    Cunningham, Christine M.
    Eghbali, Mansoureh
    SEX-SPECIFIC ANALYSIS OF CARDIOVASCULAR FUNCTION, 2018, 1065 : 31 - 47
  • [3] RNA epigenetics and cardiovascular diseases
    Dorn, Lisa E.
    Tual-Chalot, Simon
    Stellos, Konstantinos
    Accornero, Federica
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2019, 129 : 272 - 280
  • [4] Epigenetics and microRNAs in cardiovascular diseases
    Colpaert, Robin M. W.
    Calore, Martina
    GENOMICS, 2021, 113 (02) : 540 - 551
  • [5] Mitochondrial epigenetics in aging and cardiovascular diseases
    Mongelli, Alessia
    Mengozzi, Alessandro
    Geiger, Martin
    Gorica, Era
    Mohammed, Shafeeq Ahmed
    Paneni, Francesco
    Ruschitzka, Frank
    Costantino, Sarah
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2023, 10
  • [6] From air pollution to cardiovascular diseases: the emerging role of epigenetics
    Micheu, Miruna-Mihaela
    Birsan, Marius-Victor
    Szep, Robert
    Keresztesi, Agnes
    Nita, Ion-Andrei
    MOLECULAR BIOLOGY REPORTS, 2020, 47 (07) : 5559 - 5567
  • [7] Regulation of microRNAs by epigenetics and their interplay involved in cancer
    Liu, Xiaolan
    Chen, Xiaoyan
    Yu, Xinfang
    Tao, Yongguang
    Bode, Ann M.
    Dong, Zigang
    Cao, Ya
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2013, 32
  • [8] The Interplay between Autophagy and Redox Signaling in Cardiovascular Diseases
    Botanska, Barbora
    Dovinova, Ima
    Barancik, Miroslav
    CELLS, 2022, 11 (07)
  • [9] Environmental exposures, epigenetics and cardiovascular disease
    Baccarelli, Andrea
    Ghosh, Sanjukta
    CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2012, 15 (04): : 323 - 329
  • [10] Translational Perspective on Epigenetics in Cardiovascular Disease
    van der Harst, Pim
    de Windt, Leon J.
    Chambers, John C.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2017, 70 (05) : 590 - 606