Interferon-Free Hepatitis C Virus Therapy

被引：12

作者：

Pawlotsky, Jean-Michel ^{[1
,2
]}

机构：

[1] Hop Henri Mondor, Dept Virol, Natl Reference Ctr Viral Hepatitis B C & D, F-94010 Creteil, France

[2] INSERM U955, F-94010 Creteil, France

来源：

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE | 2020年 / 10卷 / 11期

关键词：

SOFOSBUVIR PLUS RIBAVIRIN; INFECTION; LIVER; CRYOGLOBULINEMIA; LEDIPASVIR; EFFICACY; SAFETY;

D O I：

10.1101/cshperspect.a036855

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with similar to 71 million chronically infected individuals worldwide. Treatment of patients with HCV-related liver disease has advanced considerably thanks to the development of new direct-acting antiviral drugs that are now administered as highly potent, safe, and well-tolerated combinations with a high barrier to resistance. International organizations, such as the European Association for the Study of the Liver, the American Association for the Study of Liver Diseases jointly with the Infectious Diseases Society of America, or the World Health Organization have published detailed treatment guidelines. With these therapies becoming more and more widely available, elimination of hepatitis C as a public health threat by 2030 can now be envisaged in several countries. In other regions, better screening, diagnosis, and linkage to care will be necessary to achieve this ambitious goal.

引用

页码：1 / 13

页数：13

共 27 条

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