Antinociceptive and anti-inflammatory activity of Sida rhomboidea leaves

被引:23
作者
Venkatesh, S
Reddy, YSR
Suresh, B
Reddy, BM
Ramesh, M
机构
[1] JSS Coll Pharm, Ooty 643001, India
[2] Kakatiya Univ, Univ Coll Pharmaceut Sci, Warangal 506009, Andhra Pradesh, India
关键词
Sida rhomboidea; Malvaceae; organic extracts; phytochemical screening; antinociceptive activity; anti-inflammatory activity;
D O I
10.1016/S0378-8741(99)00016-1
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Various organic extracts of Sida rhomboidea leaves were studied for antinociceptive and anti-inflammatory activity at a dose of 200 mg/kg. Ethyl acetate extract has shown significant (P < 0.01) antinociceptive activity. Percentage inhibition of edema by butanolic extract (33.05, P < 0.001) is comparable to that of phenylbutazone, 100 mg/kg inhibition (38.83%). Phytochemical screening of the extracts indicated the presence of alkaloids, steroids and/or triterpenoids and their glycosides, tannins, flavonoids and their glycosides, carbohydrates and absence of cardiac glycosides. (C) 1999 Published by Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:229 / 232
页数:4
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