Short homodimeric and heterodimeric coiled coils

被引：47
作者：
Dong, H
Hartgerink, JD
机构：
[1] Rice Univ, Dept Chem, Houston, TX 77005 USA
[2] Rice Univ, Dept Bioengn, Houston, TX 77005 USA
来源：
BIOMACROMOLECULES | 2006年 / 7卷 / 03期
关键词：
D O I：
10.1021/bm050833n
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this communication, we discuss the design, synthesis, and characterization of four peptides which are able to self-assemble into five different homo- and heterodimeric a.-helical coiled coils based on the pH of their environment. These peptides are very short, containing only 14 or 21 amino acids each, and illustrate the minimum requirements necessary to form dimeric coiled coils which are critical in a large number of biological and materials design applications.
引用
收藏
页码：691 / 695
页数：5
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