Decline in macrolide-resistant Streptococcus pyogenes isolates from French children

被引：22

作者：

d'Humieres, Camille ^{[1
]}

Cohen, Robert ^{[2
,3
]}

Levy, Corinne ^{[2
,3
]}

Bidet, Philippe ^{[1
]}

Thollot, Franck ^{[4
]}

Wollner, Alain ^{[2
]}

Bingen, Edouard ^{[1
]}

机构：

[1] Univ Paris 07, Hop Robert Debre, Microbiol Serv, Lab Etud Genet Bacterienne Infect Enfant EA3105, F-75019 Paris, France

[2] Assoc Clin & Therapeut Val de Marne ACTIV, St Maur Des Fosses, France

[3] Ctr Hosp Intercommunal Creteil, Microbiol Serv, F-94010 Creteil, France

[4] Assoc Francaise Pediat Ambulatoire, F-54270 Esseys Les Nancy, France

来源：

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY | 2012年 / 302卷 / 7-8期

关键词：

Streptococcus pyogenes; Macrolide; Resistance; Children; GROUP-A STREPTOCOCCI; IN-VITRO ACTIVITY; ERYTHROMYCIN RESISTANCE; ANTIMICROBIAL RESISTANCE; MOLECULAR EPIDEMIOLOGY; TELITHROMYCIN; SURVEILLANCE; ANTIBIOTICS; PREVALENCE; GENOTYPES;

D O I：

10.1016/j.ijmm.2012.09.001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We studied the macrolide resistance and serotypes of 585 group A streptococcus (GAS) isolates collected from French children with pharyngitis. Nineteen isolates (3.2%) were erythromycin-resistant and harbored the following resistance genes: 31.6% mef(A), 15.8% erm(A), and 52.6% erm(B). The 19 isolates included 7 different emm types (4, 1, 11, 2, 28, 12, and 77) and 7 corresponding multilocus sequence types. The current fall in macrolide consumption has led to a very low rate of GAS macrolide resistance. (C) 2012 Elsevier GmbH, All rights reserved.

引用

收藏

页码：300 / 303

页数：4

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