Short Report: Surveillance and Molecular Characterization of Group A Rotaviruses in Goroka, Papua New Guinea

被引：8

作者：

Horwood, Paul Francis ^{[1
]}

Luang-Suarkia, Dagwin ^{[1
]}

Bebes, Sauli ^{[1
]}

Boniface, Karen ^{[2
]}

Datta, Siddhartha Sankar ^{[3
]}

Siba, Peter Max ^{[1
]}

Kirkwood, Carl Dunn ^{[2
]}

机构：

[1] Papua New Guinea Inst Med Res, Goroka EHP441, Eastern Highlan, Papua N Guinea

[2] Royal Childrens Hosp, Murdoch Childrens Res Inst, Enter Virus Res Grp, Melbourne, Vic, Australia

[3] World Hlth Org, Western Pacific Reg Off, Port Moresby, Papua N Guinea

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2012年 / 87卷 / 06期

基金：

英国医学研究理事会;

关键词：

POLYMERASE CHAIN-REACTION; STRAINS; DIARRHEA; CHILDREN; VACCINE; EPIDEMIOLOGY; HIGHLANDS; G12; REASSORTMENT; SPECIFICITY;

D O I：

10.4269/ajtmh.2012.12-0234

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In this study, we investigated the molecular epidemiology of group A rotaviruses in cases of acute gastroenteritis in Goroka, Papua New Guinea. From April 2008 through November 2010, 813 diarrheal stool samples were collected from children < 5 years of age hospitalized with acute gastroenteritis. Rotavirus antigen was detected in 31.2% of samples using a commercial enzyme-linked immunosorbent assay. Genotyping revealed the presence of the globally circulating strains G1P[8] (50.0%), G3P[8] (23.0%), and G2P[4] (8.2%). The globally emerging strains G9 and G12 were detected in 1.2% and 6.1% of samples, respectively. Mixed infections were detected in a high proportion of samples (11.9%), with 9.0% and 3.7% of samples displaying multiple G and P genotypes, respectively.

引用

页码：1145 / 1148

页数：4

共 31 条

[31] Purification, Characterization, Molecular Cloning, and Expression of a New Aminoacylase from Streptomyces mobaraensis That Can Hydrolyze N-(Middle/Long)-chain-fatty-acyl-L-amino Acids as Well as N-Short-chain-acyl-L-amino acids
Koreishi, Mayuko
Nakatani, Yasuyuki
Ooi, Manami
Imanaka, Hiroyuki
Imamura, Koreyoshi
Nakanishi, Kazuhiro
[J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2009, 73 (09) : 1940 - 1947

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