Short Report: Surveillance and Molecular Characterization of Group A Rotaviruses in Goroka, Papua New Guinea

被引:8
|
作者
Horwood, Paul Francis [1 ]
Luang-Suarkia, Dagwin [1 ]
Bebes, Sauli [1 ]
Boniface, Karen [2 ]
Datta, Siddhartha Sankar [3 ]
Siba, Peter Max [1 ]
Kirkwood, Carl Dunn [2 ]
机构
[1] Papua New Guinea Inst Med Res, Goroka EHP441, Eastern Highlan, Papua N Guinea
[2] Royal Childrens Hosp, Murdoch Childrens Res Inst, Enter Virus Res Grp, Melbourne, Vic, Australia
[3] World Hlth Org, Western Pacific Reg Off, Port Moresby, Papua N Guinea
基金
英国医学研究理事会;
关键词
POLYMERASE CHAIN-REACTION; STRAINS; DIARRHEA; CHILDREN; VACCINE; EPIDEMIOLOGY; HIGHLANDS; G12; REASSORTMENT; SPECIFICITY;
D O I
10.4269/ajtmh.2012.12-0234
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In this study, we investigated the molecular epidemiology of group A rotaviruses in cases of acute gastroenteritis in Goroka, Papua New Guinea. From April 2008 through November 2010, 813 diarrheal stool samples were collected from children < 5 years of age hospitalized with acute gastroenteritis. Rotavirus antigen was detected in 31.2% of samples using a commercial enzyme-linked immunosorbent assay. Genotyping revealed the presence of the globally circulating strains G1P[8] (50.0%), G3P[8] (23.0%), and G2P[4] (8.2%). The globally emerging strains G9 and G12 were detected in 1.2% and 6.1% of samples, respectively. Mixed infections were detected in a high proportion of samples (11.9%), with 9.0% and 3.7% of samples displaying multiple G and P genotypes, respectively.
引用
收藏
页码:1145 / 1148
页数:4
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