Assessment of cognitive flexibility in real life using virtual reality: A comparison of healthy individuals and schizophrenia patients

被引：34

作者：

Han, Kiwan ^{[1
]}

Kim, In Young ^{[2
]}

Kim, Jae-Jin ^{[1
,3
,4
]}

机构：

[1] Yonsei Univ, Coll Med, Severance Biomed Sci Inst, Seoul 120749, South Korea

[2] Hanyang Univ, Dept Biomed Engn, Seoul, South Korea

[3] Yonsei Univ, Coll Med, Gangnam Severance Hosp, Dept Psychiat, Seoul 120749, South Korea

[4] Yonsei Univ, Coll Med, Inst Behav Sci Med, Seoul 120749, South Korea

来源：

COMPUTERS IN BIOLOGY AND MEDICINE | 2012年 / 42卷 / 08期

关键词：

Virtual reality; Cognitive flexibility; Decision making; Schizophrenia; OBSESSIVE-COMPULSIVE DISORDER; EXECUTIVE FUNCTION; NEUROCOGNITIVE DEFICITS; INHIBITION; ACTIVATION; EXPERIENCE; SCALE;

D O I：

10.1016/j.compbiomed.2012.06.007

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

To date, cognitive flexibility has been measured only using neuropsychological tasks, and has not been tested using more ecologically valid task due to methodological limitations. In this study, a virtual reality task was developed to evaluate cognitive flexibility in a real life situation and performance on this task was compared between 30 healthy individuals and 30 schizophrenia patients. Compared to healthy controls, a greater number of schizophrenia patients made concrete decisions, and their decision-making times were negatively correlated with the severity of their negative symptoms. These findings indicate that virtual reality can be an ecologically valid measurement of cognitive flexibility. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：841 / 847

页数：7

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